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《Chinese Journal of Blood Transfusion》 2018-03
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The application of autologous blood retransfusion after total knee arthroplasty: A Meta-analysis

XIONG Shengren;YU Guangshu;XIONG Guosheng;LIN Yanbin;Department of Orthopaedics,Fuzhou Second Hospital Affiliated to Xiamen University;  
Objective To assess the clinical efficiency,safety and potential advantages of autologous blood retransfusion after total knee arthroplasty. Methods Related publications,including Chinese and English,were retrieved( from January01,1990 to June 01,2017) from Pub Med,Cochrane Library,EMBASE,BIOSIS,Ovid,CNKI,Vip,Wanfang Data,and manual search with randomized controlled trials( RCT) to compare the use of autologous blood retransfusion after total knee arthroplasty. Methodological quality of the trials was assessed by the modified Jadad standard. Qualified publications were extracted. Statistical software Revman 5. 1. 0 was used for data-analysis. Results A total of 7 randomized controlled trials were included,including 6 English and 1 Chinese from a total 858 literatures. There were 4 studies that qualified as level A and 3 studies as level B. The results of meta-analysis showed that the hemoglobin of perioperative period presented no significant difference. The rate of blood transfusion was lower in the autologous blood retransfusion group( RR = 0. 39,95% CI: 0. 28 to0. 55,P0. 00001). No significant difference on complication( RR = 0. 86,95% CI: 0. 41 to 1. 79,P = 0. 68) between group was found. Conclusion In general,the use of allogeneic blood will reduce if the autologous blood transfusion is used. The patient with low hemoglobin should consider autologous blood transfusion if the condition allows.
【Fund】: 福州市卫生计生科技计划项目(2016-S-wq2);; 福建省自然科学基金(2016J01597)
【CateGory Index】: R457.1;R687.4
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