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《Chinese Journal of Blood Transfusion》 2018-03
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Coagulation function monitoring of regular plateletpheresis donors by thrombelastography

FENG Qing;YE Jun;LI Chunyan;GUO Beijie;KONG Fuxian;Zhejiang Blood Center;  
Objective The aim of this study is to systematically evaluate the effect of regular plateletpheresis on the coagulation and platelet function of donors by thrombelastography( TEG).Methods We selected 105 cases of regular plateletpheresis donors in Zhejiang blood center dating from August 2016 to July 2017 as the regular donation group,which was further divided into 3 subgroups based on donation counts: 6—11,12—17 and 18—24 donations annually. We also selected 32 cases of first-time plateletpheresis donors as the control group. The blood samples were collected before donation. Coagulation and platelet functions were tested using TEG( Haemonetics company,Braintree,MA,USA). Platelet counts were tested by a SYSMEX XS-800 i blood cell analyzer.Results R time,K time,α-Angle,MA value、PLT、MPV and PDW of the regular donation group were all within the normal ranges. Compared with the control group,All indexes had no statistical significance( P0. 05). All parameters were not statistically significant among the three subgroups( P0. 05). The correlation between plateletpheresis frequency and R、K、α-Angle、MA、PLT、MPV、PDW values was not statistically significant.Conclusion The thrombelastography can assess the coagulation and platelet function of regular plateletpheresis donors systematically,effectively and accurately. Regular plateletpheresis had no significant impact on the coagulation and platelet function of donors.
【Fund】: 浙江省医药卫生科技计划基金(2015KYA068)
【CateGory Index】: R446.1
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