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《Chinese Journal of Blood Transfusion》 2019-01
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Distribution of A_2, MNS, P, and Kell serological phenotype in the Kazak nationality living in northern Xinjiang of China

QIU Fen;Gulibahati;WEN Jun;TIAN Xuemei;Asmuguli;PAN hui;Department of transfusion, Kuitun Hospital of Xinjiang′s Ili Kazak Autonomous Prefecture;Department of Transfusion, Xinjiang Uygur Autonomous Region People′s Hospital;Department of transfusion, Friendship Hospital of Xinjiang′s Ili Kazak Autonomous Prefecture;  
Objective To understand the polymorphisms of the A_2 subtype, MNS, P, and Kell phenotypes in the Kazak population of northern Xinjiang and to establish data on rare blood group antigens in the Kazakh population.Methods 6 862 unrelated individuals in the Kazak population of northern Xinjiang were randomly selected. The antigen of A, B, A_1, M, N, P_1 and K was detected by blood type serological saline test tube method. The antigen of S, s and K was detected by the card type microcolumn gel antiglobulin method. Results 1) A_2 subtype, the detection rate in type A was 7.08%, and the detection rate in AB type was 21.79%. 2) The allele frequencies of MNS, P and Kell blood type were successively:M=0.566 8, N=0.433 2, S=0.186 0, S=0.814 0, P_1=0.284 8, P_2=0.715 2, K1=0.009 6, K2=0.990 4. using the χ~2 test, The Observation value and expectation of genotype frequency distribution were compared. Conform to the Hardy-Weinberg genetic rule(P0.05). 3) Detecting the rare gene phenotype of MNS blood group system in Kazak population, namely S-s-14 cases, with a frequency of 1.16%. 4) The frequency of K antigen in the Kell blood group system was 1.92%, and 1 cases of rare KK homozygote were detected, with a frequency of 0.034%. Conclusion The gene frequency distribution of A_2 subtype, MNS, P and Kell blood type of the Kazakh population in North Xinjiang in Xinjiang region have the characteristics of own ethnic. The MNSs blood type has a unique genetype. and Kell blood type K antigen positive rate is significantly higher than that of the Han nationality.
【Fund】: 新疆维吾尔自治区自然科学基金(201442137-24)
【CateGory Index】: R457.11
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【Citations】
Chinese Journal Full-text Database 3 Hits
1 ZHANG Rong;TIAN Li;LI Xiaojuan;YAO Zhiqiang;LI Hong;MAO Rui;CIREN Yangji;DA Zhen;LI Guoqing;ZHAIXI Dunzhu;WU Wei;SONG Ning;Institute of Blood Transfusion,Chinese Academy of Medical Sciences;Tibeten Blood Center;;Gene polymorphism of 10 blood group systems in Tibetans,China[J];中国输血杂志;2014-05
2 LUO Hong-qing, YUAN Xia, LIU Kai-bo, et al (Shaoguan Blood Center, Shaoguan 512025, Guangdong Province, China);Distribution of ABO,Rh,MN,P and Jk~(a-b-) Blood Groups in Population in Shao guan Prefecture,Guangdong Province,China[J];中国生物制品学杂志;2008-06
3 Xiao Heng 1 Hao Luping 2 Zhang Mingqiu 3 Xiao Chunjie 1(1 Department of Biology, College of Life Sciences and Chemistry,Yunnan University,Kunming 650091) (2 Institute of Genetics, Chinese Academy of Sciences, Beijing 100101) (3 Yunnan Family Pla;DISTRIBUTION OF FOUR RED CELL BLOOD GROUP SYSTEMS IN JINO,BLANG AND LAHU ETHNIC GROUPS[J];人类学学报;2000-03
【Co-citations】
Chinese Journal Full-text Database 7 Hits
1 Huang Lu;Chen Lihong;Zhuang Yunfang;Liu Lihua;Liang Yanlian;Heyuan Blood Center;;Gene frequencies of MN blood group in Heyuan,Guangdong[J];国际医药卫生导报;2014-14
2 XIN Youpan,TIAN Li,SONG Ning,ZHANG Rong,YAO Zhiqiang,CHEN Jingxian.Institute of Blood Transfusion,Chinese Academy of Medical Sciences&Pekiny Union Medical College,Chengdu 610052,China;Molecular genetic analysis of ABO,MNS,Duffy,Diego,Lutheran,Kidd,Dombrock and Colton blood group systems in Sichuan Yi population[J];中国输血杂志;2013-01
3 Zhang Wen1,Li Defa2,Wang Hongmei2,Wu Yueping2,Cao Ke2,Liu Xingang1,Jiang Yihong1, Yang Jing1,Shao Yanli1,Chen Yuesheng1(1.Department of Blood Transfusion;2.Department of Laboratory,Shenzhen Children′s Hospital, Shenzhen Guangdong 518026,China);Screening of JK(a-b-) phenotypes of Kidd blood group in children of certain area[J];国际检验医学杂志;2011-17
4 LI Meng,XU Hui-hui,GAO Jin-yu,LEI Lian-cheng(College of Animal Science and Veterinary Medicine,Jilin University,Changchun 130062,China);Development of an Optimized ELISA for the Quantitative Detection of Protein in the Milk[J];中国畜牧兽医;2011-04
5 WU Wei-Jian,LUO Hai-Ling,HUANG Chang-Hai,GUO Ru-Hua,YU Jin-Lin.Foshan Blood Center,Foshan 528000,China;Investigation of the distribution of Rh blood group in voluntary blood donors in Foshan,Guangdong province,China[J];中国免疫学杂志;2010-02
6 WU Wei-jian, SU Kai, WEI Bo(Foshan Blood Center, Foshan 528000, Guangdong Province, China);Derivation of A Modified Method for Estimation of Gene and Haplotype Frequencies of Rh Blood Group System[J];中国生物制品学杂志;2009-12
7 HUANG Xiu-qiong,NIURong-xiang ZHOUPing,et al (Department of Physiology,Dali College,Dali,Yunnan671000,China);Survey and Analysis of Four Group Antigens on Red Blood Cell on Nu Ethnic[J];大理学院学报;2004-03
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Yang Bo,LV Yun-lai,MA Hong-li,et al.The Blood Center of Luoyang,Henan,Luoyang 471000;The Study on Duffy Genotyping of Han Population in Luoyang[J];临床输血与检验;2012-01
2 YANG Tong-han,ZHU Xiang-ming,CHU Zhan-guang,et al.Kunming Blood Center,Yunnan Kunming 650106;Study on the Main Red Cell Blood Groups of Dulong Nationality from Yunnan Province[J];临床输血与检验;2011-03
3 ZHUO Xiaofu1 ZHUO Chuanshang1 GUO Yongjian1(Fujian Blood Center,Department of Transfusion of Fujian Medical University,Fuzhou,350004,China);The gene polymorphisms of RHD and RHCE loci in Han population in Fuzhou[J];临床血液学杂志(输血与检验版);2011-01
4 BAI Xu-Hua,LAN Jiong-Cai1,GONG Xiao-Yan,CUI-Li,ZHOU Hua-You1 Blood Center of Xinjiang Production & Construction Corps,Urumqi 830002,Xinjiang Uygur Autonomous Region,China;1Department of Blood Transfusion,Nanfang Hospital,Guangzhou 510515,Guangdong Province,China;Study on RHCE Genotyping of Rh Blood Group in Uygur Nationality of Xinjiang in China[J];中国实验血液学杂志;2010-05
5 ZHAO Xiao-ming,LI Zhi-qiang.The Sixth Affiliated People's Hospital of Shanghai Jiaotong University,Shanghai 200233;Research of Genetic Polymorphism of Rare Blood Group System in Shanghai Han Population[J];临床输血与检验;2009-03
6 LIU Yanchun XU Jianfeng WU Minhui(Jiangsu Provnice Blood Center,Nanjiang,210042,China);Study on dombrock blood group Do~a and Do~b genotyping by PCR-SSP technique[J];临床血液学杂志(输血与检验版);2009-03
7 DENG Shizhen, ZENG Meimei, YAN Kangfeng, et al. Panyu Blood Center, Guangzhou, 514100 China;A study of the distribution of Jk(a-b-) phenotype in the blood donors of Panyu district,China[J];中国输血杂志;2007-01
8 SUN Zhi-gang, DING Mei, WANG Bao-jie, HUANG Hong-wu (School of Forensic Science, China Medical University, Shenyang 110001, China);RHCE Genotyping in Chinese Han from north and Li from South[J];法医学杂志;2006-04
9 Liu Mengli,Jiang Dongling2琇iu Sheng (Blood Group Laboratory,Shannxi Blood Center,Xi'an 710061,China);Diego blood group typing of Han nationality in Xi'an City[J];西安交通大学学报(医学版);2003-04
10 Zhu Zeyan,Sheng Wei,Cheng Hoping,et al.Shanghai Blood Center,Shanghai,200051,China;Rare blood group screening among Chinese blood donors in Shanghai area[J];中国输血杂志;2002-04
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