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《CHINESE JOURNAL OF BLOOD TRANSFUSION》 1996-04
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ENGLISH OF ORIGINAL ARTICLES ( Study on Length Polymorphology of Enlarging Fragment at Apo B 3 Locus in Population Cohort of Han Nationality in Chengdu Region )

Jing Qiang,et al (West China University of Medical Sciences)  
The length polymorphology analysis of enlarging fragment at Apo 3 locus in 200 unrelated patients out of population cohort of Han nationality in Chengdu region has been performed,using the technique of analysing the length polymorphology of enlarging fragment.As a result,sixteen alleles have been found,with their fragment sizes ranging between 542 and 992 bp,gene frequencies of 0.0025~0.3750,heterozygosity of 0.79 and DP value of 0.95.Of 138 possible genotypes,43 genotypes have been found.The observed and expected values of those genotypes coincide with the Hardy Weinberg equilibrium( χ 2=2,13,df=1.0,P 0.01).The family line investigation showed that the inheritance of Apo B 3 locus follows the Mendelian Law.The sensetivity and specificity of the technique can be improved with HS PCR method.
【Fund】: 卫生部科研基金
【CateGory Index】: Q347
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【Co-references】
Chinese Journal Full-text Database 10 Hits
1 CHEN Wei-ru~* WANG Jian-zhi CHEN Liang YANG Jian SHEN Hai-ming YANG Yong-hua * Research Institute of Aeromedicine,Civil Aviation University of China,Ttanjin 300300,China;Effect of flying burthen on blood lipid level in civil aviation aircrew[J];中华劳动卫生职业病杂志;2006-12
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8 CHEN Baosheng, GUO Zhongmin , HE Ping , YE Ping , C. Buresi and G. Roizes Institute of Basic Medical Science, Beijing 100005, China (Chen BS, Guo ZM, He P and Ye P) CNRS INSERM, Montpellier, France (C. Buresi and G. Roizes) Correspond;Structure and function of alleles in the 3' end region of human apoB gene[J];Chinese Medical Journal;1999-03
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【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 Nanshan Ai (Architecture and Environment College, Sichuan University);A Study on Zang-Yi Corridor from the Hengduan mountains[J];藏学学刊;2008-00
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