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《Glass & Enamel》 2002-02
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Preparation and Application of Glass Microspheres for Radiotherapy

HUANG Wen?hai 1, QIAN Da?xing 1, ZHOU Nai 1, MAO Bo 1, GAO Ke?jia 2 (1. School of Material & Engineering, Tongji University, Shanghai 200433, China; 2. Shanghai Huangpu District Central Hospital, Shanghai, China)  
The biocompatible glass microspheres containing Y 89 and P 31 elements used for radiotherapy to cure malignant tumor can be prepared by flame spray method or liquid phase seperation technique based upon wet chemical method. These glass microspheres can emit high-energy short range β-ray due to the fact that the glass microspheres contain Y 90 and P 32 elements after neutron exposure in nuclear reactor. They are also able to enter into target organs easily to kill cancer cells because of their excellent biocompalibility, high specific activity, proper radioactive half-life, therefore they have remarkably successful therapeutic effect in clinical practice for curing hepatic cancer, gastric cancer, pancreatic huege cyst and cancer of uterus. About more than 50% of patients suffering from cancer in an advanced stage can survive for 3 years and over by curing with glass beads.
【Fund】: 国家“8 63”计划资助项目 (715 -0 2 0 -0 2 0 0 ) ;; 国家自然科学基金资助项目 (5 9172 0 75和 5 95 72 0 0 85 )
【CateGory Index】: TQ171.74
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【Citations】
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【Co-citations】
Chinese Journal Full-text Database 7 Hits
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【Co-references】
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