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《Journal of Beijing Agricultural College》 2006-01
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Effect of Porcine Circovirus Type 2 Infection on Fc Receptor Number and Phagocytosis of Porcine Alveolar Macrophage

ZHOU Shuang-hai, ZHAO Dong-sheng , GUO Xin, YANG Han-chun ( College of Veterinary Medicine, China Agricultural University, Beijing 100094,China; Beijing Agricultural College, Beijing 102206,China)  
In order to explore the effects of porcine circovirus type 2 (PCV2) infection on some bioactivity of Porcine alveolar macrophage (PAM) , PAMs were collected at different days post inoculation (PI) from forty-day-old healthy conventional piglets inoculated oro-nasally with PCV2 BF strain, the phagocytosis ability of PAMs was detected by phagocytosing chicken erythrocytes, and Fc receptor expressed on PAMs was determined by EA assay. Results showed Fc receptor number expressed on PAMs decreased to the neap at 3d PI, as compared to the control, then increased and recovered at 14d PI. PAMs phagocytosis ability shared the same changes. These results demonstrated that the ability of PAMs to phagocytose and eliminate pathogens weakened transiently after infection with PCV2,
【Fund】: 教育部跨世纪人才基金(2003)资助项目
【CateGory Index】: S858.28
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Chinese Journal Full-text Database 1 Hits
1 ZHOU Shuang-hai1,2,ZHAO Dong-sheng2,YANG Han-chun2 *,GUO Xin2,SI Xing-kui2(1.Department of Animal Science and Veterinary Medicine,Beijing Agricultural College,Beijing 102206,China;2.College of Veterinary Medicine,China Agricultural University,Beijing 100094,China);Porcine Circovirus Type 2 Infection Could Induce No Apoptosis of Porcine Alveolar Macrophage[J];Journal of Beijing Agricultural College;2006-04
【Citations】
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