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The calmative and sex hormone-like effect of Cordyceps militaris(L)Link(Cantherea pernyi)

Liu Jie, Yang Xu, Chen Zhcng, Liang Manyi, Li Jingluo(Dept,of Pharmacol,N. Bethune Univ.of Med.Sci;*Jilin Prouincial Institute of Silkworm Breeding)  
Cordyceps militaris(L)Link’s decoction possesses a calmative effect on mice;when used in combination with pentobarbital,it synergized the hypnotic action of the latter, ex-hibiting an anti-convulsive effect,increasing the anti-fatigue ability of the experimental animals,and the plasm content of cortisol and testesterone was elevated obviously. It increased not onlythe weight of the preputial glands, the seminal vesicle and prostate, but also the seminal vesicle-prostate of the castrated mice,exerting a male-hormone-like effect. The results showed that it’seffect is quite similar to that of cordyceps sinesis(Berk)Sacc.
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