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《Journal of Bethune Medical Science》 2014-03
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Asthma patients in acute episode and remission: analysis and correlation study of adiponectin level changes,pulmonary function and blood gas

ZOU Huibiao;QIN Pingxiang;XIANG Yueqiao;Department of Respiratory Diseases,Leliu Hospital of Shunde District of Foshan;  
Objective To discuss asthma adiponectin level changes of acute episode and remission patients and pulmonary function,blood gas analysis and correlation studies. Methods Patients were divided into acute phase group,remission group and control group( n = 50,each). Double antibody clamp method was used to determine blood gas adiponectin,RV% pred,FEV1% pred,PaO2,and PaCO2. Results Levels of Adiponectin,RV% pred,FEV1% pred,PaO2of the 3 groups showed statistical difference( P 0. 05),but PaO2of the 3 groups showed no statistical difference( P 0. 05). Levels of Adiponectin,RV% pred,FEV1% pred,PaO2of the acute phase group were lower than those of the remission group and the control group( P 0. 05),but RV% pred level was higher than that of control group( P 0. 05). Adiponectin level after treatment in acute phase group was significantly higher than that before treatment( P 0. 01). Conclusion Serum adiponectin level of asthma patients is significantly lower than that of normal people,and the acute phase patients tend to have a bigger decrease than the remission patients and adiponectin may play a protective role in the process of controlling asthma and may be related to the pulmonary function and PaO2of the patients.
【CateGory Index】: R562.25
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