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《Journal of Bethune Medical Science》 2014-04
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Clinical observation of allylestrenol drug treatment of recurrent spontaneous abortion during different periods

YE Feixue;TIAN Yuhua;Department of Gynecology and Obstetrics,Fourth People’s Hospital of Huizhou;  
Objective To analyze the clinical efficacy of allylestrenol treatment of recurrent spontaneous abortion during different periods. Methods Clinal data of 172 patients with recurrent spontaneous abortion were analyzed and the patients were divided into control group( n = 43) and the observation group( n = 129) according to different dosages. The control group was given ogesterone treatment,and the observation group was divided into three subgroups( n = 43,each) according to different drug treatment periods and received allylestrenol treatment. The drug giving periods of subgroup A,B,and C were after ovulation,two weeks after conception,three weeks after conception respectively. Clinical efficacy and term delivery rates of each group were compared. Results The total effective rate of observation subgroup A was higher than that of subgroup C( P 0. 01) and term delivery rates of observation group were higher than that of control group( P 0. 01),term delivery rate of observation subgroup A was higher than that of subgroup B( P 0. 05) and C( P 0. 01). Conclusion The best periods of allylestrenol treatment of recurrent spontaneous abortion is after ovulation,which can improve clinical treatment outcomes and the success rate of term delivery.
【Fund】: 广东省惠州市科技计划项目(编号:20140804)
【CateGory Index】: R714.21
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