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《Journal of Baotou Medical College》 2018-09
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Expressions and changes of D-Dimer and coagulation index in different pregnancy periods

YANG Ke;The Maternal and Children Health Care Hospital in Jian'an District of Xuchang;  
Objective: To study the expressions and changes of D-Dimer and coagulation index in different pregnancy periods. Methods: 289 normal pregnant women were selected as the pregnancy group,while 150 cases of normal non-pregnant women who were examined during the same period were selected as the control group. According to the three periods of early,middle and late pregnancy,the pregnant women were divided into three groups. The D-Dimer and four indexes of coagulation fibrinogen( Fg),activated partial thromboplastin time( APTT),thrombin time( TT),prothromin time( p T) of the two groups were compared. Results:There was no statistical difference in the age,gravidity,parity of pregnant women in the three periods of early,middle and late pregnancy. The D-Dimer and Fg index increased progressively in the three periods of early,middle and late pregnancy. PT showed a declining trend. The APTT and TT in the late period were significantly lower than those in the middle and early periods. The D-Dimer and Fg index in pregnancy group were higher than those in the control group,and the three indexes of APTT,TT and p T were lower than those of the control group. Conclusion: The results of D-Dimer and four indexes of coagulation in different pregnant women are different. Dynamic monitoring of D-two dimer and coagulation in pregnant women can help to prevent abnormal bleeding and complications during childbirth and postpartum.
【CateGory Index】: R714
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