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《Journal of Binzhou Medical College》 2001-01
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STUDY ON RELATIONSHIP BETWEEN THE CIRCADIAN VARIATION OF CORTISONE AND THE PATHOGENESIS OF NOCTURNAL ASTHMA

Wang Xiaozhi,Li Yunhua,Gao Fuquan, et al (Affiliated Hospital of Binzhou Medical College,Binzhou,Shandong Province,256603)  
Objective:To explore the relationship between the circadian variation of cortisone and the pathogenesis of nocturnal asthma.Methods: Blood levels of cortisone and PEF were measured during acute exacerbation in 30 nocturnal asthmatic patients (not treated with glucocorticoid,during stabilization in 30 asthmatic ptaients,and at 4 AM and 4 PM in 30 normal control subjects.Results: There was normal level and circadian rhythm of cortisone during acute exacerbation in nocturnal asthmatic patients when compared with control group ( P 0 05).Conclusion:Nocturnal worsening symptoms of asthma could not be caused by reduction of serum cotisone concentration.
【Fund】: 山东省教委资助!课题 (J97K0 8)
【CateGory Index】: R562.25
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【Co-citations】
Chinese Journal Full-text Database 10 Hits
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