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《Journal of Binzhou Medical College》 2003-01
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Zhang Xuezhi (Clinical Laboratories,Central Hospital of Shengli Petroleum Administrative Bureau,Dongying 257034,China)  
Objective:To investigate the relationship among serum HBV DNA quantification,hepatitis clinical changes and HBV markers in hepatitis patients.Methods:HBV DNA extracted from the serum in 96 hepatitis patients by PCR was quantified by ELISA.Results:The association of HBV DNA qualitative and quantitative analysis was identical in 96 hepatitis patients(95 2%).HBV DNA concentration went down rapidly after treatment with antivirus medicine in 20 acute hepatitis patients.According to HBV DNA levels from high to low,they were severe hepatitis,chronic hepatitis,chronic light hepatitis and acute hepatitis respectively.Serum HBV DNA concertration in HBeAg positive group was significantly higher than that in HBeAg negative group( P 0 001).Conclusion:Serum HBV DNA quantification has an important value for evaluating changes of hepatitis,effects of treatment,and prognosis in hepatitis patients.
【CateGory Index】: R446.5
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