Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Binzhou Medical College》 2003-01
Add to Favorite Get Latest Update

CLINICAL STUDY ON SERUM HBV DNA QUANTIFICATION WITH PCR AND ELISA IN HEPATITIS PATIENTS

Zhang Xuezhi (Clinical Laboratories,Central Hospital of Shengli Petroleum Administrative Bureau,Dongying 257034,China)  
Objective:To investigate the relationship among serum HBV DNA quantification,hepatitis clinical changes and HBV markers in hepatitis patients.Methods:HBV DNA extracted from the serum in 96 hepatitis patients by PCR was quantified by ELISA.Results:The association of HBV DNA qualitative and quantitative analysis was identical in 96 hepatitis patients(95 2%).HBV DNA concentration went down rapidly after treatment with antivirus medicine in 20 acute hepatitis patients.According to HBV DNA levels from high to low,they were severe hepatitis,chronic hepatitis,chronic light hepatitis and acute hepatitis respectively.Serum HBV DNA concertration in HBeAg positive group was significantly higher than that in HBeAg negative group( P 0 001).Conclusion:Serum HBV DNA quantification has an important value for evaluating changes of hepatitis,effects of treatment,and prognosis in hepatitis patients.
【CateGory Index】: R446.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 2 Hits
1 Wang Hong;Wang Shengliang; Wan Chengsong; Peng Huaguo; Zhang Wenbing(Institute of Molecular Biology Diagnosis and Department of Microbiology, First Military Medical University, Guangzhou, 510515);Quantification and analysis of HBV DNA in hepatitis patient serum using sandwich hybridisation-ELISA assay on microplate[J];JOURNAL OF FIRST MILITARY MEDICAL UNIVERSITY;1999-04
2 MIAO Xiaohui , KONG Xiantao, QI Zhongtian. Changzheng Hospital, Second Military Medical University, Shanghai 200003, China;A method for quantification of hepatitis B Virus genome by enzyme linked solid phase sandwich hybridization[J];CHINESE JOURNAL OF INFECTIOUS DISEASES;2000-01
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Zhao Shousong,Cui Zhuo,Wang Shumin,et al. Department of Infectious Disease,Affiliated Hospital of Bengbu Medical College,Bengbu 233004;Investigation on TT virus infection of hemodialysis patients in Wanbei area[J];Anhui Medical Journal;2001-01
2 XU Wen-Sheng , MIAO Xiao-Hui, WU Wen-Ya, HAO Yong (Department of Infectious Diseases, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China);3'-terminus shifted bases degeneracy primers increasing sensitivity of polymerase chain reaction[J];Academic Journal of Second Military Medical University;2003-04
3 YE Xiao guang,WANG Ruo lun 1,GUO Hai bo 2 (Department of Infectious Diseases, 1Department of Pharmacy; 2Department of Laboratory,Second Affiliated Hospital of Guangzhou Medical College,Guangzhou 510260);Detection of YMDD motif Mutations in the Lamivudine-Untreated Chronic Hepatitis B[J];Academic Journal of Guangzhou Medical College;2002-02
4 JIANG Wei,LIU Li-qiu(Department of Nephrology,Attached Hospital of Medical School,Qingdao University,Shangdong Qingdao 266003,China);Effect of content of hepatitis B virus DNA in the serum on the pathologic change in hepatitis B virus associated-glomerulonephritis[J];Journal of Central South University(Medical Sciences);2008-09
5 ZHAO Shou song ZHAO Jiu fa, GAO Chun-ming et al Department of Infectious Disease,Affiliated Hospital of Bengbu Medical College,Anhui(233004);To Study Transfusion transmttted Virus(TTV)Co-in5ection in Other Hepatttis and The Genotypes[J];Chinese Journal of Clinical Hepatology;2001-03
6 Zhan Yü lin, Li Guo hang, Yang Zhi yuan (Department of infectious diseases,Longgang Centrol Hospital,Shen zhen 518116,China);Study on Prevalence and Genotypes of TT Virus Infection in Intravenous Drug Users[J];Practical Clinical Medicine;2001-02
7 XIANG Yan-gen,SHI Guo-min.Changsha Central Hospital of Hu'nan provinces,Changsha 410004;PCR microplate hybridization-ELISA for identification of tubercle bacillus DNA[J];Bulletin of Chinese Antituberculosis Association;2003-04
8 WANG Hong, WAN Chengsong, WANG Shengliang, et al. Institute of Molecular Biology Diagnosis, First Military Medical University, Guangzhou 510515, P. R. China;Study on genotypes of HBV DNA using PCR microplate hybridization-ELISA[J];Chinese Journal of Microbiology and Immunology;2001-02
9 ZHOU Dongyao, WANG Hong, WANG Shengliang, et al.Department of Clinical Laboratory, Zhujiang Hospital, First Military Medical Univeristy, GuangZhou 510282, P.R. China;Clinical and experimantal study on Lumivudine resistance[J];Chinese Journal of Microbiology and Immunology;2001-S1
10 CHEN Xiang,LIU Ling,LIANG Li-hong,TANG Jun-hong.Department of Clinical Laboratory,First People's Hospital of Zhaoqing,Guangdong,526021,China;The infection and pathogenicity of TT virus among different populations[J];Chinese Journal of Primary Medicine Pharmacy;2005-05
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved