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《Journal of Chengde Medical College》 1999-04
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EFFECTS OF TOTAL FLAVONOID FROM STEMS AND LEAVELS OF SCUTELLARIA BAICALENSIS ON GLUTATHIONE PEROXIDASE ACTIVITY AND LIPID PEROXIDE CONTENT IN MICE

Li Suting et al Department of Biochcmistry  
Objective:To study the effects of total flavonoid(TF) extracted from stems and leaves of Scutellaria baicalensis on glutathione peroxidase(GSH PX) activity and lipid peroxide(LPO) content.Methods:By random sampling,40 Kunming mice were equally divided into four groups of 3 dosage groups and one control group.The TF of 200mg.kg 1 ,400mg.kg 1 and 800mg.kg 1 were respectively administered ig to the 3 dosage groups once a day for 3 weeks(distilled water as controls).Three weeks later,the brain and liver homogenates prepared with the 40 experimental animal were used for determining GSH PX activity by chemical colorimetric method and LPO content by improved TBA method.Resuts:Compared with the contral group,TF increased the GSH PX activity and markedly decreased the LPO content.Conclusion:The TF has antioxidative effect.
【CateGory Index】: R285.5
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