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《JOURNAL OF CHENGDE MEDICAL COLLEGE》 2000-03
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STUDIES ON RELATIONSHIP BETWEEN PREGNANCY TROPHOBLASTIC TUMORS AND VIRUS

KH2D][WT5BZ]LI Yu hong,et al [WT5BX](Department of Pathology,Chengde Medical College,Hebei Chengde 067000,China)[KH2D][WT5HZ]  
Object:To determine the relationship between trophoblastic tumors and virus.Methods:Human papillomavirus(HPV)and human cytomegalovirus(HCMV) were detected with polymerase chain reaction(PCR) in 82 cases of trophoblastic tumor,Corresponding ultrastructural changes was studied with electron microscopy(EM).Results:NO HPVDNA was detected in 30 cases of normal placentas with PCR method,while among the 82 cases of trophablastic tumors,only 1 case was HPVDNA positive.There was no significant difference between these two groups.HCMV was studied in 27cases of trophablastic tumor but all of the cases were negative.Yet ultrastructurally,a series of changes likely suggested that virus infection could be found in trophoblastic tumor cells.Conclusion:Though HPV and HCMV were rarely found in trophoblastic tumors by PCR method,the possibility of other virus existence could not be excluded on the base of EM observation.
【CateGory Index】: R730.231
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 Zhang Ruixiang; Liu Sheng; Ma Weijunet al( Laboratory of Electron Microscopy, Chengde Medica; College, Chengde 067000);The ultrastructure of intermediate type trophoblast cell[J];CHINESE JOURNAL OF PATHOLOGY;1995-05
【Co-citations】
Chinese Journal Full-text Database 10 Hits
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【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 Zhang Ruixiang; Liu Sheng; Ma Weijunet al( Laboratory of Electron Microscopy, Chengde Medica; College, Chengde 067000);The ultrastructure of intermediate type trophoblast cell[J];CHINESE JOURNAL OF PATHOLOGY;1995-05
2 Zhang Ruixiang(Chengde Medical College,Chengde);An Ultrastructural Dynamic Study of Trophoblast Cells in Human Placenta[J];Acta Academiae Medicinae Sinicae;1992-02
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