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《Journal of Chengde Medical College》 2001-01
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INFLUENCE OF YISHEN JIANGZHUO DECOCTION ON SOD ACTIVITIES AND MDA CONTENTS IN RATS OF CEREBRAL ISCHEMIA REPERFUSIN

MENG Fan xing,et al (Department of Pathphysiology,Chengde Medical College,Hebei Chengde 067000,China)  
Objective:To investigate the effect of Yishen Jiangzhuo decoction on superoxide dismutase(SOD) activities and malondialdehyde(MDA) contents in rats with injury of cerebral ischemiareperfusion.Methods:After the model of ischemia reperfusion injury was performed based on hypotension,the rats were administed ig with Yishen Jiangzhuo decoction once a day for seven days.After the last ig 60 minusts,the rats were all decapitated and extract the brain to assay SOD activities and MDA contents.Results:Yishen Jiangzhuo decoction can significantly increase SOD activities and decrease MDA contents compared with model group.Conclusion:Yishen Jiangzhuo decoction in a degree have the effect of antagonized the cerebral ischemia reperfusion injury.
【Fund】: 河北省科委科研基金资助!(课题号 982 761 87D)
【CateGory Index】: R285.5
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