Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Chengde Medical College》 2004-01
Add to Favorite Get Latest Update

PROTECTIVE EFFECTS OF TOTAL GLUCOSIDES OF PAEONY AND EXTCACT FROM ANGELICA SINENSIS ON EXPERIMENTAL IMMUNOLOGICAL LIVER INJURY

CHEN Xiang-qing,WANG Qin-mao,FANG Hua-wu,et al (Dept.Of Pharmacy,Anhui Provinical Hospital,Anhui Hefei 230001,China)  
Objectuve:To study the protective effects of total glucosides of paeony (TGP) and extract from Angelica Sinensis (EAS) on experimental immunological liver injury.Method:Mouse immunological liver injury was induced by BCG and LPS.Result:The decrease of ALT,AST,ALP and the increase of GSH in serum,which were caused by BCG and LPS,could be antagonised by TGP and EAS.The hepato-cellular degeneration and necrosis induced by BCG and LPS could also be diminished.The optimal dosage is TGP(200 mg·kg -1 ·d -1 ,7d,ig) plus EAS (153.4g·kg -1 ·d -1 ,7d,ig).Couclusion:Pre-treatment with TGP and EAS moderately prevents the liver damage induced by BCG and LPS. [
【CateGory Index】: R285
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 4 Hits
1 H Wang, RX Peng, RK Wang and R Kong (Department of Pharmacology, Hubei Medical University, Wuhan 430071);ANTAGONIZING EFFECT OF SODIUM FERULATE ON THE CHANGES OF HEPATIC ANTIOXIDATIVE FUNCTION INDUCED BY ETHANOL IN MICE[J];ACTA PHARMACEUTICA SINICA;1997-07
2 Department of Pharmacology, Hubei University of Medical Sciences (Wuhan 430071) Li Ying and Peng Renxiu;Protective Effects of Sodium Ferulate and Ethanol Sediments from Danggui (Angelica sinensis) on Immunological Liver Injury[J];CHINESE TRADITIONAL AND HERBAL DRUGS;2000-04
3 DAI Li-Ming, CHEN Xue-Guang, XU Shu-Yun (Dept Of Pharmacology, Anhui Medical University, Hefei, 230032);Protective effects of total glucosides of paeony on experimental hepatitis[J];Chinese Pharmacological Bulletin;1993-06
4 ZHANG Hong,WEI Wen-Shu,CHEN Min-Zhu,XU Shu-Yun (Inst Clinical Pharmacology,Anhui Medical University,Hefei 230032);Immunomodulatory effects of total glucosides of Paeonia lactifiora and their mechanisms[J];Chinese Journal of Pharmacology and Toxicology;1990-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 SHI Yan,DING Xiang (1.The Second Hospital of Jiangsu Huai’an, Huai’an 223002, China; 2.The First Hospital of Jiangsu Lianyungang, Lianyungang 222002, China);Observation on effectiveness of MTX and TGP on rheumatic arthritis with childrenshiyan[J];Anhui Medical and Pharmaceutical Journal;2004-06
2 Peng Chuanhui, Cheng Peng, Xu Zhide, et al Department of Gastroenterology, 153 Hospital, PLA, Zheng Zhou 450043;RELATIONSHIP BETWEEN ESOPHAGEAL DYNAMICS AND SERUM NITRIC OXIDE IN CIRRHOSIS PATIENTS WITH ESOPHAGEAL VARICES[J];Journal of Clinical Hepatology;2000-03
3 Anhui Technical Teachers College Fengyang 233100) LIU Han\|zhen 1\ LIU Ai\|rong 1\ LI Xiao\|liang 1\ LI yi\|song 2\;2 Anhui angriculture college Hefei 230031\;;The Chemical Composition and Pharmacodynamics Resersh Recent Development about Peeled Root of Herbaceous Penoy[J];Journal of Anhui Agrotechnical;2001-04
4 Zheng Qinyue; Guan Xiaoju; Li Shutong (Department of Pharmacology, College of Pharmacy, Second Military Medical University, Shanghai, 200433);The effects of Siwu Tang and its ingredients on the level of mouse serolysin[J];ACADEMIC JOURNAL OF SECOND MILITARY MEDICAL UNIVERSITY;1995-04
5 Yang huiqing,Tian Gen Department of ophthalmoiogy,The peace Hospital;The Effect of Nitric Oxide on Hepatic Fibrosis in rat[J];Journal of Changzhi Medical College;2002-02
6 CHEN Xiang qing,WANG qin mao,FANG Hua wu,SU Cui mei (Dept. Of Pharmacy, Anhui Provincial Hospital,Anhui Hefei 230001,China);PROTECTIVE EFFECTS OF TOTAL GLUCOSIDES OF PAEONY AND EXTRACT FROM ANGELICA SINENSIS ON EXPERIMENTAL HEPATITIS[J];Journal of Anhui Traditional Chinese Medical College;2002-03
7 SONG Yu-hong, LIU Qiang, CHEN Yu-yao, Lü Zhi-pingSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China;Protective effects of Hongbeiyegen against immunological liver injury in mice[J];Journal of Southern Medical University;2008-03
8 Liao Kejun.The First Hospital of Changde City,Changde City,Hunan Province 415003;Study on the Nitric Oxide and Tumor Necrosis Factor in Serum of Patients with Accute Hepatitis and Liver Cirrhosis[J];JOURNAL OF CHINESE PHYSICIAN;1998-07
9 Wu Limao 1,Li Lianda 2,Liu Hong 2,Ning Keyong 2,Li Yikui 2 (1.College of Pharmaceutlcal Science,Zhejiang University,Hangzhou 310031,China; 2.China Academy of Traditional Chinese Medicine, Xiyuan Hospital, Beijing 100091,China);Studies of the Guiyuan Fang and Autologous Bone Marrow Stem Cells Transplantation on Hepatic Injury and Fibrosis[J];Engineering Science;2004-07
10 LI Ning LIU Li GAO Chong-kai (Guangdong College of Pharmacy,Guangzhou 510006,China);Determination of paeoniflorin in controlled porosity osmotic pump tablets of total glucosides of paeony by HPLC[J];Journal of Guangdong College of Pharmacy;2007-06
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Fang Jianqiao,Kan Fangju Zhejiang College of TCM,Hangzhou(310053);Influences of Electroacupuncture on Pain Threshold and Antiˉcollagen Antibody,ILˉ1βin CIA Rats[J];Journal of Zhejiang College of Tcm;2003-01
2 DONG Jun 2, LIU Jian Yong 1, WAN Mo Bin 1, TANG Xian Tuan 3, ZHU Ju Zhen 1 (1. Department of Infectious Disease, Changhai Hospital, Second Military Medical University, Shanghai 200433, China; 2. Department of Gastroenterology, Traditional Chinese;Cellular immunoregulation of Traditonal Chinese Medicine Huangqi in treating patients with chronic hepatitis B by intravenous injection[J];Academic Journal of Second Military Medical University;2001-07
3 Anhui Technical Teachers College Fengyang 233100) LIU Han\|zhen 1\ LIU Ai\|rong 1\ LI Xiao\|liang 1\ LI yi\|song 2\;2 Anhui angriculture college Hefei 230031\;;The Chemical Composition and Pharmacodynamics Resersh Recent Development about Peeled Root of Herbaceous Penoy[J];Journal of Anhui Agrotechnical;2001-04
4 CHU Ai wu 1* ,CUI Yue hong 2,LIU Wen bo 3,JIANG Shao jun 3 (1 Department of Pharmacy,the Affiliated Hospital of Binzhou Medical College;2 Hospital of Binzhou Industrial School; 3 Electron Microscopy Laboratory,Binzhou Medical College,Shandon;Mechanism of oleic acid-induced percutaneous penetration enhancement: an ultrastructural study[J];Journal of Chinese Electron Microscopy Society;2002-02
5 JIANG Feng*, LIU Jian-bai. *Department of Rheumatology and Immunology, The Third Hospital of Huzhou, Zhejiang 313000, China;An observation on clinical efficacy in fibromyalgia syndrome[J];Chinese Journal of Rheumatology;2004-12
6 Xie Juan, Huang Nenghui, Li Chengxiu, et al. Guizhou Province Public Health School for Medical Workers, Guiyang,550001;Effect of Han-Dan Gan-Le on acute hepatic injury of cholestasis in mice[J];Guizhon Medical Journal;2001-02
7 GuoShungen, JiangTao, ZhangWei, ZhaoFujian,ZhaoLiyun, Bai Jinwen (Lab. of Cytology and Biochemistry, Beijing University of Traditional Chinese Medicine, Beijing 100029, China) \;〔;INVESTIGATION ON PROTECTING LIVER BY HUOXUEHUAYUFANG WITH TECHNIC OF HISTOCHEMISTRY AND IMMUNOHISTOCHEMISTRY[J];Chinese Journal of Histochemistry and Cytochemistry;2004-03
8 CAO Lan-fang*, ZHAO Yu, MAO Hai-ying, GU Yue-ying, ZHOU Wei, XU Hong, ZHOU Li-jun, JIANG Jin-jin. *Department of Rheumatology, Renji Hospital, Shanghai Second Medical University, Shanghai 200001, China;The clinical efficacy and safety of TGP treatment in juvenile idiopathic arthritis[J];Chinese Journal of Rheumatology;2006-02
9 ZHANG Hao ,ZHU Ping,WANG Yanhong,et al. Department of Clinical Immunology,Xijing Hospital,Fourth Military Medical University, Xi′an 710032, China;Study on Th1/Th2 balance in patients with rheumatoid arthritis[J];CHINESE JOURNAL OF RHEUMATOLOGY;2000-02
10 ZHOU Jialing,ZHU Qi.Department of Rheumatology,Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai 200052, China;Effects of acupuncture on the rheumatoid arthritis[J];CHINESE JOURNAL OF RHEUMATOLOGY;2000-03
【Secondary Citations】
Chinese Journal Full-text Database 7 Hits
1 Wu Dongfang; Peng Renxiu; Wang Yushan; et al(Department of Pharmacology, First Affiliated Hospital,Hubei Medical University, Wuhan 430071, China);Effects of Sodium Ferulate on Bromobenzene-induced Hepatic Damage in Mice[J];ACTA ACADEMIAE MEDICINAE HUBEI;1994-03
2 Wang Yongxiang ,Wang Weiqun & Huang Jiping et al (Dept. of Phar., Anhui Medical University , Hefei);THE PROTECTIVE EFFECT OF TGPs ON ACUTE LIVER INJURY INDUCED BY CARBON TETRACHLORIDE IN MICE[J];Chinese Pharmacological Bulletin;1988-06
3 WANG Hui, PENG Ren-Xiu (Department of Pharmacology, Hubei Medical University, Wuhan 430071, China);Sodium ferulate alleviated paracetamol-induced liver toxicity in mice[J];Acta Pharmacologica Sinica;1994-01
4 Zhou Shuqin et al;The Study of pyrimidine as an Interferon Type Ⅰ Inducer[J];Acta Universitis Medicinalis Nahui;1986-02
5 Xia Xueyan and Peng Renxiu (Department of Pharmacology, Hubei University of Medical Science,Wuhan 430071);Effects of Chinese Angelica Tuber (Angelica sinensis) Ethanol Sediments on Mice Spleen and Thymus Lymphocytes Proliferation in vitro[J];CHINESE TRADITIONAL AND HERBAL DRUGS;1999-02
6 DFWu,RX Peng and H Wang (Department of Pharmacology,Hubei Medical University,Wuhan 430071);SODIUM FERULATE ALLEVIATES PREDNISOLONE INDUCED LIVER TOXICITY IN MICE[J];ACTA PHARMACEUTICA SINICA;1995-11
7 CHEN Min-zhu, JIN Wen-zhen, DAI Li-min, XU Shu-yun (Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230028);Effects of luteolin on inflammation and immune function[J];Chinese Journal of Pharmacology and Toxicology;1986-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved