Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Chengde Medical College》 2010-01
Add to Favorite Get Latest Update

EFFECTS OF BREVISCAPINE PRETREATMENT ON MYOCARDIAL CELLS APOPTOSIS OF CAR-DIAC ISCHEMIA/REPERFUSION RATS

GONG Ming-yu,LIU Yong-ping,LI Fang,et al (Department of Biochemistry,Chengde Medical College,Hebei Chengde 067000,China)  
Objective:To investigate protective effects of breviscapine pretreatment on myocardial cells apoptosis of ischemia/reperfusion injury rats.Methods:40 SD rats were divided into sham operation group,model group and 2 breviscapine pretreatment groups at random (n=10).The rats in breviscapine pretreatment groups were intraperitoneally injected 25 mg/kg/d and 50 mg/kg/d breviscapine respectively 1 week prior to ischemia/reperfusion;while the rats in other two groups were given NS instead.Myocardial ischemia/reperfusion injury model was established by ligating the anterior interventricular branch of the left coronary artery:ligation 30 minutes and reperfusion 2 hours.The AnnexinⅤ-EGFP/PI staining and flow cytometry were used to detect the apoptosis of myocardial cells.Results:Breviscapine pretreatment could decrease apoptosis ratio of myocardial cells of ischemia /reperfusion injury rats obviously (P0.05,P0.01).Conclusions:Breviscapine pretreatment can protect the myocardial cells of ischemia/reperfusion injury rats by inhibiting apoptosis of myocardial cells.
【CateGory Index】: R285
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 1 Hits
1 De Hong Huang,Cheng Yin Wang,Jian Hong Huang,Yu Ye,Xiu Hui Chen,Department of Neurology,Guangzhou Hospital of Traditional Chinese Medicine,Guangzhou 510130,Guangdong Province,China;Point-injection therapy combining baihui acupuncture with parenteral solution of breviscapine for post-cerebral infarction depression[J];Chinese Journal of Clinical Rehabilitation;2004-28
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 ZHU Yong_mei,ZHONG Jin_yi ˇ ,ZHANG Li_hua (Institute of Nutrition,Medical College of Qingdao University,Qingdao266021,Shandong,China);The Effect of HPP on Abnormal Expression of Mice Hepatic Cells POD and Caspase-3[J];Carcinogenesis,Teratogenesis & Mutagenesis;2006-04
2 ZHU Guo-qi,TANG LI-jian,WANG Lei,SU Jing-jing,WANG Ning,PENG Dai-yin,LI Qing-lin(Anhui College of Traditional Chinese Medicine & Anhui Key Laboratory of Modern Chinese Materia Medica,Anhui Hefei 230038,China);Study on Baicalin Induced Apoptosis of Human Breast Cancer Cell Line MDA-MB-231[J];Journal of Anhui Traditional Chinese Medical College;2008-02
3 ZHAO Xin, SONG Jin dan*Key Laboratory of Cell Biology,Ministry of Public Health of China,China Medical Unviersity,shenyang 110001,P.R.China;Clotrimazole Induced Apoptosis in Human Colon Cancer Cell Line CCL229[J];Chinese Journal of Cancer;2002-06
4 ZHANG Ming sheng1*, YUAN Hong yin1, XIONG Bin1, DENG Qin1, TANG Zhi jiao2, XIA Dong21.Department of Oncology, Zhongnan Hospital of Wuhan University,Wuhan 430071, P.R.China2.Department of Pathology,Medical College, Wuhan University, Wuhan 430071,;Expression and Clinical Significance of IGF-Ⅱ mRNA and Bcl-2 Protein in Colorectal Adenocarcinomas[J];Chinese Journal of Cancer;2002-11
5 Li Jin Quan1,Chen Rui Chuan2,Cai Ke Xia2,Ye Zhi Yun11.Department of Biology,2. Cancer Research Center,Life Science School of Xiamen University, Xiamen, Fujian, 361005, P.R.China;Apoptosis of Human Gastric Cancer Cell Induced by Photochemical Riboflavin[J];Chinese Journal of Cancer;2003-03
6 LIANG Tong, CHEN Mei-Jun, ZHOU Ke-Yuan, TANG Xu-Dong, WANG Xu-Guang Institute of Biochemistry and Molecular Biology, Guangdong Medical College, Zhanjiang,Guangdong,524023, P.R.China;Induction of Apoptosis in Human Nasopharyngeal Carcinoma Cell Line CNE-2Z by Curcumin[J];Chinese Journal of Cancer;2004-12
7 YAN Xiao-Jian1,2, LIANG Li-Zhi1,2, ZENG Zong-Yuan1,3, SHI Zhi1,4, FU Li-Wu1,41. State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, 510060, P. R. China2. Department of Gynecology, Cancer Center,Sun Yat-sen University,Guangzhou, Guangdong, 510060, P. R. China2. Department of Head and Neck Surgery, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong, 510060, P. R. China3. Research Department, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong, 510060, P. R. China;Effect of Survivin shRNA on Chemosensitivity of Human Ovarian Cancer Cell Line OVCAR3 to Paclitaxel[J];Chinese Journal of Cancer;2006-04
8 MEI Chuan zhong,SHEN Ji long,CHEN Yong,LI Bai qing (Department of Microbiology and Parasitology,Anhui Medical University,Hefei,Anhui 230032,China);Apoptosis of γδT cells and αβT cells induced by ceramide[J];Journal of Bengbu Medical College;2004-03
9 ZHOU Lei,YU Dong-hong,WANG Ping,CHEN Ze-nong(Department of Pathology,Bengbu Medical College,Bengbu 233030,China);Experimental study for effect of sulindac for gastric cancer cell BGC-823[J];Journal of Bengbu Medical College;2007-02
10 TANG Chang-fa,ZHOU Jie(Institute of Physical Education, Hunan Normal University, Changsha 410012,Hunan China);Exercise and Apoptosis[J];Journal of Beijing University of Physical Education;2004-01
China Proceedings of conference Full-text Database 2 Hits
1 Yang Ruirui Feng Feng Guo Hongyu (Beijing Sport University,Beijing 100084);Ubiquitin Proteasome Pathway and Skeletal muscle Apoptosis in Exercises[A];[C];2007
2 XIE Jian-qun Shanghai University of Traditional Chinese Medicine(Shanghai 201032);Ulcerative colitis TCM treatment based on syndrome differentiation And research progression of Qing Chang Shuan in treating ulcerative colitis[A];[C];2007
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 Li Xiao (Department of Neurological medicine, General Hospital, Tianjin Medical University 300052);The Senile Post-cerebral-infarction Depression and Its Related Factors[J];Tianjing Medical Journal;1999-06
2 Ci-Xiong Zhou,Xiao-Lin Su,Xiao-Zhong Yang,Xue-Chang Xiao,Hong-Wen Zhao Ci-Xiong Zhou,Xiao-Lin Su,Xiao-Zhong Yang,Xue-Chang Xiao,Hong-Wen Zhao,De partment of Neurology,Shenzhen People's Hospital 518020,Guangdong Province,Chin a;Effect of psychological nursing on the rehabilitation of post-stroke depression[J];Chinese Journal of Clinical Rehabilitation;2004-16
3 Jia Yanbin and Zhou Qianzhang. Department of Psychiatry, The First Affiliated Hospital, Jinan University Medical College. Shipai, Guangzhou(510630).;Clinical study on correlation factors in depression state following first stroke.[J];CHINESE JOURNAL OF NERVOUS AND MENTAL DISEASES;1998-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved