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《Journal of Chengde Medical College》 2013-01
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INFLUENCE OF QINGKAILING INJECTION ON PROLIFERATION OF MOUSE SPLEEN T AND B LYMPHOCYTES

XING En-hong,SHAO Xue-zhai,WANG Xu-dan,et al(The Affiliated Hospital of Chengde Medical College,Hebei Chengde 067000,China)  
Objective:To study the influence of Qingkailing injection(QKL) on proliferation of mouse spleen T and B lymphocytes in vitro.Methods:Concanavalin A was added to mouse spleen lymphocytes to activate T lymphocytes and LPS to activate B lymphocytes.MTT method was used to observe the effects of QKL of different concentration on mouse spleen T and B lymphocytes proliferation.Results:QKL of different concentration(1/3200 and above) could obviously inhibit proliferation of spleen B lymphocytes,and showed dose dependent(P0.01).High concentration QKL(1/400 and above) could inhibit proliferation of spleen T lymphocytes,while low concentration QKL(below 1/800) could promote proliferation of spleen T lymphocytes(P0.01).Conclusions:QKL can regulate immune reaction by influencing the proliferation of T and B lymphocytes.
【Fund】: 承德市科技发展计划项目(200922070)
【CateGory Index】: R285.5
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