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《Journal of Chengde Medical College》 2013-01
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LI Dan,CHANG Hong-min,ZHAO Lei,et al(Chengde Medical College,Hebei Chengde 067000,China)  
Objective:To observe the changes of Caspase-3 protein in small intestine and muscle tissue of trichinella spiralis mice.Methods:Henan strain trichinella spiralis infected Kunming mice model was established,and Caspase-3 protein expression were detected in small intestine(infected 3d,5d and 7d) and muscle tissue(infected 4w,5w and 6w) respectively.Results:With extension of infection time,the expression of Caspase-3 protein in small intestine increased during developmental process of trichinella spiralis adult(P0.05).The expression of Caspase-3 protein in muscle tissue of infected 5w was the highest during developmental process of trichinella spiralis larvae(P0.05).Conclusions:Trichinella spiralis infection can cause increasing of Caspase-3 protein expression in small intestine and muscle tissue of mice,moreover has relations with infection time.
【CateGory Index】: R382
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