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《Journal of Chengde Medical College》 2014-01
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CLINICAL ANALYSIS OF CASPOFUNGIN IN TREATMENT OF HEMATOLOGICAL MALIGNANCIES COMBINED INVASIVE PULMONARY ASPERGILLOSIS INFECTION

LIANG Li;SHEN Xu-liang;ZHANG Mei-xiang;Department of Hematology,Peace Hospital Affiliated to Changzhi Medical College;  
Objective: To evaluate the clinical efficacy and safety of caspofungin in treatment of hematological malignancies combined invasive pulmonary aspergillosis(IPA) infection.Methods: 49 hematological malignancies combined IPA infection patients(2008.1-2012.12) that were diagnosed by CT and galactomannan test were treated with caspofungin. The clinical effi cacy and safety of caspofungin were evaluated according to clinical curative effect standard. Results:The total effective rate of 49 patients was 91.84%(45/49) after caspofungin treatment; and the incidence of drug related adverse events was 18.37%(9/49).Conclusions:Caspofungin has good antifungal activity,and it is a safe and effective drug for treating hematological malignancies combined IPA infection.
【CateGory Index】: R519
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