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《Materials Review》 2014-16
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Research on Co-loading Drug Release Properties in Nanoparticles Embedded Microcapsules

TANG Xiaolin;LIU Yuangang;WANG Shibin;SUN Xuezhan;College of Chemical Engineering,Huaqiao University;Institute of Biomaterials and Tissue Engineering,Huaqiao University;  
A total of two drugs were embedded in nanoparticles embedded microcapsules(NEMs),and the joint release properities between them were investigated.Results showed that when co-loaded capecitabine(CAP)and bevacizumab/papain,multi-chamber structure of NEMs exhibited the effect of delaying the release of CAP and the cumulative release rate of macromolecules was higher.What was more,these two drugs had very good orderly release results in NEMs in the middle and latter processes.However,co-loading CAP and methotrexate,multi-chamber structure of NEMs had limited suppression of drug release and basic trend of the two drugs was consistent.
【Fund】: 国家自然科学基金(31000441);; 福建省自然科学基金(2013J01189)
【CateGory Index】: R943
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【Citations】
Chinese Journal Full-text Database 6 Hits
1 LIU Yuan-Gang1,2,MAO Hong-Hao1,WANG Shi-Bin1,2,SUN Xue-Zhan1 (1.College of Chemical Engineering, 2.Institute of Biomaterials and Tissue Engineering,Huaqiao University,Xiamen 361021,China);Preparation and Characterization of a Novel Embolic Nano-in-Micro Drug Delivery System[J];Chemical Journal of Chinese Universities;2011-11
2 LIU Yuan-gang,SUN Xue-zhan,WANG Shi-bin(College of Chemical Engineering,Huaqiao University,Xiamen 361021,China);Preparation and characterization of NEMs loading γ-globulin[J];Journal of Functional Materials;2013-08
3 WU Wen-bing1,2,YANG Wan-shen1,WANG Xian-xiang1(1.College of Life Science,Sichuan Agricultural University,Ya'an 625014;2.Department of Environmental Science,Kashgar Teacher's College,Kashgar 844000,China);Immobilization of Papain on Amino Magnetic Microsphere and Its Application Study[J];Biotechnology;2010-05
4 AN Fu rong,GE Sheng rong, ZHU De qiu (Department of Clinical Pharmacy, Renji Hospital, Shanghai Second Medical University, SHANGHAI 200001, China);Pharmacology and clinical use of cepecitabine[J];Chinese Journal of New Drugs and Clinical Remedies;2002-08
5 WU Jian-feng1,YU De-hong2,FANG Chao2,JIA Lian-shun1,LI Jia-shun1,XU Guo-hua1(1.Department of Orthopedics,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China;2.Department of Pharmacology,College of Basic Medical Sciences,Shanghai Jiao Tong University,Shanghai 200025,China);Preparation and Release Study of Methotrexate Loaded PLGA-Nanocapsules in Vitro[J];Chinese Pharmaceutical Journal;2010-02
6 NI Tian-gen,GUAN Quan-lin,WANG Na,GAO Chen,ZHOU Xin,YANG Han-teng(Department of Oncological Surgery,First Hospital of Lanzhou Universtiy,Lanzhou 730000,China);Bevacizumab plus chemotherapy as first-line therapy for metastatic colorectal cancer:a systematic review of the efficacy and safety[J];Tumor;2010-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 SUN Xuezhan1,LIU Yuangang1,2,WANG Shibin1,2,CHEN Aizheng1,2,LUO Zhiyong1(1.College of Chemical Engineering,Huaqiao University,Xiamen 361021,China;2.Institutes of Pharmaceutical Engineering,Huaqiao University,Xiamen 361021,China);Properties of embolic microcapsules loading capecitabine[J];Acta Materiae Compositae Sinica;2011-05
2 LIU Yuan-gang,SUN Xue-zhan,WANG Shi-bin(College of Chemical Engineering,Huaqiao University,Xiamen 361021,China);Preparation and characterization of NEMs loading γ-globulin[J];Journal of Functional Materials;2013-08
3 Meng Yugang,Liang Chunyan,Ceng Yachang,Zeng Yachang,An Ming.(Department of Gynecology and Obstetrics,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China);EXPRESSION AND CLINICAL SIGNIFICANCE OF SERUM VEGF-A AND ITS RECEPTOR VEGFR-2 IN PATIENTS WITH CERVIAL CARCINOMA[J];Journal of Guangxi Medical University;2013-01
4 JIANG Xiang-de;WANG Lei;LIU You-ru;SHI Zhen-shan;XU Ying;Department of Oncology,Bozhou People's Hospital;;Capecitabine combined with oxaliplatin and docetaxel in treatment of advanced gastric cancer[J];Journal of Bengbu Medical College;2014-04
5 ZHU Ren-fa1,CHEN Shi-yun2,HE Yong2(1.Department of Chemical and Materials Engineering,Hefei University,Hefei 230022,China;2.Hefei Huijia Chemical Sci & Tech Co.LTD,Hefei 230051,China);A New Synthesis Method of Capecitabine[J];Chinese Journal of Synthetic Chemistry;2008-01
6 Zou rong,Zhao Pingping,Chen xi,Qu Yuanjiao,Cao Yilin,Liu Taowen(Department of Oncology,Nanxishan Hospital of Guangxi Zhuang Autonomous Region,Guilin 541002,China);Relationship Between Serum VEGF-A,VEGFR-2 and Lymph Node Metastasis in Nasopharyngeal Carcinoma[J];Journal of Basic and Clinical Oncology;2012-03
7 FAN Guodong,ZHANG Chunmei Key Laboratory of Auxiliary Chemistry & Technology for Chemical Industry,Ministry of Education;College of Chemistry and Chemical Engineering,Shaanxi University of Science and Technology,Xi'an 710021,China;Medical Applications of Polylactic Acid:Recent Advances in Research[J];Science & Technology Review;2010-19
8 Fang Xiugui 1,Zhang Keshuai 2 (No.463 Hospital of the People's Liberation Army,Shenyang,Liaoning,110042);Clinical Observation on Therapeutic Effect of Capecitabine Associated with Platinum Medicament on Advanced Gastrointestine Carcinoma[J];Anti-tumor Pharmacy;2012-02
9 HUANG Weisun LIU Chaoying XU Junying Department of Oncology,the Affiliated People's Hospital of Nanjing Medical University,Wuxi City,Najing Province,Wuxi 716000,China;Clinical Analysis of Bevacizumab Combined with Irinotecan in the Treatment of M etastatic Colorectal Cancer[J];China & Foreign Medical Treatment;2013-09
10 Chong En Fa;Sun Chun Yan;Zhang Peng Cheng;Yancheng Dong Yang Biological Products Company,LTD;Chemistry and Chemical Engineering Jnstitate,Southeast University;;Synthesis of 1,2,3-tri-o-acetyl-5-deoxidation-D-Ribofuranose by D-Ribose[J];Chemical Industry Times;2013-11
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 XIN Meihua LI Mingchun ZHANG Xingsong DENG Jun (College of Material Science and Engineering,Huaqiao University,The Key Laboratory for Functional Materials of Fujian Higher Education,Quanzhou 362021);Preparation and adsorption character of the novel alkylated chitosan microspheres[J];Chinese Journal of Materials Research;2008-05
2 ZHENG Hang,CHEN Jin-zhang,LIAO Wang-jun,LUO Rong-cheng Center of Oncology,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;Efficacy of Avastin in combination with irinotecan for metastatic colorectal cancer[J];Journal of Southern Medical University;2006-05
3 Zhang Zhi-Chao, Yuan Cui, Wan Qian-Hong*(College of Pharmaceuticals and Biotechnology, Tianjin University, Tianjin 300072);Surface Modification of Magnetic Silica Microspheres and Its Application to the Isolation of Plant Genomic Nucleic Acids[J];Chinese Journal of Analytical Chemistry;2007-01
4 YU Wei-Ting~1,LIU Xiu-Dong~1,LI Xiao-Xia~2,Qi Wen-Tao~1,REN Dong-Wen~1,MA Xiao-Jun~1*(1.Laboratory of Biomedical Material Engineering,Dalian Institute of Chemical Physics,Chinese Academy of Sciences,Dalian 116023,China;2.College of Materials Science Engineering,Sichuan University,Chengdu 610064, China);Effect of pH of Chitosan Solution on Properties of Sodium Alginate-Chitosan Microcapsules with Cells[J];Chemical Journal of Chinese Universities;2006-01
5 SHAO Feng-Wei,CAI Yu-Rong,YAO Ju-Ming(Key Laboratory of Advanced Textile Materials and Manufacturing Technology of Ministry of Education, College of Materials and Textile,Zhejiang Sci-Tech University,Hangzhou 310018,China);Porous Hydroxyapatite Nanoparticles as a Carrier of Ascorbic Acid[J];Chemical Journal of Chinese Universities;2010-06
6 HUANG Wei,WANG Ping,WANG Wei,ZHANG Yue,ZHANG Chuang-Nian,TIAN Qin,WANG Xiu-Hua,LIU Yuan,YUAN Zhi(Key Laboratory of Functional Polymer Materials,Ministry of Education,Institute of Polymer Chemistry,Nankai University,Tianjin 300071,China);Preparation of Glycyrrhetinic Acid-modified PEG-PLGA Nanoparticles and the Affinity Evaluation on Hepatoma Cells[J];Chemical Journal of Chinese Universities;2011-02
7 LIU Yuan-Gang1,2,MAO Hong-Hao1,WANG Shi-Bin1,2,SUN Xue-Zhan1 (1.College of Chemical Engineering, 2.Institute of Biomaterials and Tissue Engineering,Huaqiao University,Xiamen 361021,China);Preparation and Characterization of a Novel Embolic Nano-in-Micro Drug Delivery System[J];Chemical Journal of Chinese Universities;2011-11
8 LIU Yuan-gang,WANG Shi-bin,WANG Ying(College of Materials Science and Engineering,Huaqiao University,Quanzhou 362021,China);Membrane strength investigation of a novel poly-L-arginine group microcapsule[J];Journal of Functional Materials;2009-01
9 ZHANG Xu1,2,GU Zhi-peng1,XU Yuan-ting1,LI Hua1,YU Xi-xun1,2(1.College of Polymer Science and Engineering,Sichuan University,Chengdu 610065,China; 2.Suzhou Institute of Sichuan University,Suzhou 215123,China);Preparation of oxidized alginate sodium cross-linked chitosan scaffold for drug delivery[J];Journal of Functional Materials;2011-05
10 WANG Chun,YANG Liansheng,FU Xiong(School of Light Industry and Food Sciences,South China University of Technology,Guangzhou 510640,Gangdong,China);Preparation and characterization of water-soluble chitosan nanoparticles as BSA delivery system[J];Chemical Industry and Engineering Progress;2006-12
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