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《Materials Review》 2017-13
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Preparation and Properties of a Novel Yttrium-hydroxyapatite Cement

QI Xiaopeng;LI Wen;LUO Yuanfang;YANG Hui;School of Materials Science and Engineering,Jiangxi University of Science and Technology;  
The tetracalcium phosphate(TTCP)doped with yttrium was prepared by high temperature solid state method.Then the TTCP doped with yttrium was mixed with dicalcium phosphate anhydrous(DCPA)at a molar ratio of 1∶1to form yttrium-hydroxyapatite cement(Y-HAC).The results showed that the reaction product of Y-HAC is poorly crystalline hydroxyapatite,indicating that the addition of small amount of yttrium has not changed the hydration reaction of hydroxyapatite cement(HAC).The wet compressive strength of Y-HAC increased 120%and dry compressive strength increased 85%,compared with that of HAC.The porosity of specimens has been augmented with the doping of yttrium.There exists some changes in crystallization morphology of YHAC,emerging many closely combined flaked crystals and construct a three-dimensional network structure.The in-vitro release experiment indicated that Y-HACs have very low release of yttrium.The Y-HAC might be a potential material for bone substitute,drug-loaded and bone tissue engineering.
【Key Words】: yttrium hydroxyapatite cement compressive strength bone repair
【Fund】: 江西理工大学科研基金重点课题(NSFJ2014-K10)
【CateGory Index】: R318.08
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