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CLINICAL STUDY ON THE MECHANISM OF LOWERING INTRAOCULARPRESSURE AFTER TRABECULECTOMY

Pan Peikun, et alDepartment of Ophthalmology, Third Teaching Hospital,Third Military Medical College, Chongqinq.  
Trabeculectomies were Performed in tighty patients of glaucoma of these, 23 patients had trabeculectomy on only one eye and subscleral scleretomy on the other. In order to study the mechanism of lowering intraocular pressure all cases were followed-up including the rate of control of the intraocular pressure,anterior chamber angle, formation of the filtering bleb and histological examine on excised tissue, the result showed that the rate of pressure control was 72.9%, and it was not affected whether the operated chamber angle is open or not, and whether the trabecular meshwork and Schlemm's canal were resected or not. In comparison with subscleral sclerectomy, we found that there was no significant difference between them (P0.05) ?However, the formation of filtering bleb seemed to be correlated with the control of pressure (P0.01) . Therefore, trabeculectomy is in fact a kind of filtering operation. The lowering of the pressure is the result of the diffusion of aqueous through the filter entrance under the sclerotic valve, rather than the outflow of aqueous through the section of Schlemm's canal.
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