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《Chongqing Medical Journal》 1991-05
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THE INVESTIGATION OF PIASMA 6-KETO-PGFLa AND TXB, IN PRIMARY CIIRONIC GLOMERULON EPHRITIS

Li Yi-wen et alDept. of TCM, The First AffiliatedHospital, Chongqing University of Medical sciences  
Plasma concentration of 6-Keto-PGFla(6-K-P) ,TXB2(T)and T/6-K-P were measured by RIA method in 48 cases of chronic glomerulonephritis(CGN)and 30 cases in control group. PiasmaG-K - P decreased in all patients(p0. 05,0. 01). TXB2 increased significantly in patients with nephrotic syndrome (p0. 01),but decreased in patients with renal function insufficiency(RFI)(P0. 01). T/6 - K - P were increased in all cases (p0. 05)except the RFI patients. The results showed that pathologic progression and hypercoagulation in CGN patients were closely interrelated to the unbalance of PGI2 -TXA2 and increase of T/6 -K -P. In RFI patients, the T/6 -K -P ratio may affect the presence of hypercoagulation of hypocoagulation.
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【Co-citations】
Chinese Journal Full-text Database 6 Hits
1 Xing Yi-lei, et al, Hainan Provincial People's Hospital, 570011;THE CHANGES OF THE RENAL PGI_2 AND TXA_2 IN OBSTRUCTIVE JAUNDICE RATS[J];Hainan Medical Journal;1993-03
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【Secondary Citations】
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