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The effects of autobile perfusing pancreatic duet of dog with different pressures and time on serum lysozyme and complement activies

Xie Zhixun, Wu Jiangling,Xie Bin,et al. (Research Laboratory of Molecular Biology. The General Hospital of Chengdu Military Command,Chengdu 610083)  
This study was to observe the relationship of serum lysozyme and complement activities with severify of acute pancreatitis. 30 healthy adult dogs were used as experimental animals. The seventy of acute pancreatits caused by autobile perfusing pancreatic duct of dog with different pressure and time was studied. The results showed that serum lysozyme of edematous group and necrotic group raised at 24 hour after perfusion compared with conrtol group(P 0. 01),but the complement activity in necrotic group was lower than that in conrtol group and edematous group (P 0.01 ). It is suggessted that serum lysozyme and complement avtivities play a significant role in the pathogenesis of acute pancreatitis.
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