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《Chongqing Medicine》 2006-01
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Hemodynamic alterations of central retinal artery in patients with cirrhosis

YAN Wei,FENG Yan,XIE Qi-dong(Department of Ultrasonography,Shanghai Tenth People′s Hospital,Shanghai 200072,China)  
Objective To investigate the hemodynamic alterations of central retinal artery in patients with cirrhosis.Methods The indexes of central retinal artery(CRARI),renal artery(RARI),splenic artery(SARI)were measured.Superior mesenteric artery pulsatility index(SMAPI)and portal venous velocity(PVV) were also measured in 30 cirrhotic patients,30 patients with type B chronic liver disease and 15 healthy subjects.Liver and kidney function and mean arterial pressure were also evaluated.Results CRARI was significantly increased in cirrhotic patients and CRARI was inversely correlated with PVV(r=-0.59,P0.001).The similar results were also obtained between RARI and the stage of the hepatic cirrhotic.In cirrhotic patients, there was a significant correlation between CRARI and RARI(r=-0.39,P0.01).A direct correlation was found between CRARI and SARI(r=(-0.34),P0.01).Conclusion CRA seems to be relate to the renal and splenic hemodynamics,also relate to the histology,the Doppler parameters of portal hypertension and the activity of vasoconstrictor systems.
【CateGory Index】: R575.2
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