Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chongqing Medicine》 2016-03
Add to Favorite Get Latest Update

The influence of Turbidity-reducing Granule on the intestinal immune function of rats with chronic renal failure

Wang Jian;Wang Qing;Ji Qin;Department of Nephrology,the First People′s Hospital of Yunnan;Department of Internal Medicine,Yunnan University of T.C.M;Department of Nephrology,the First Affiliated Hospital of Yunnan T.C.M University;  
Objective To establish a rat model of chronic renal failure(CRF)by using 5/6subtotal nephrectomy method,then observe and evaluate the effect of Turbidity-reducing Granule on the intestinal immune function of rats with CRF.MethodsCRF model Wistar rats were divided into high,medium and low dose group,sham operation group,and model control group.respectively given Turbidity-reducing Granule 4.05,8.10,16.20g·kg~(-1)·d~(-1).Benazepril group was given 2mL/d(1.2mg/d)Benazepril suspension fed;model control group and the sham group are saline 2mL/d orally.The rats were observed before and after treatment of signs and general condition,serum BUN,Scr changes,and pathological changes were observed under microscope.ELISA method were used to detect serum and intestinal SIgA.Results Turbidity-reducing Granule reduced the level of serum BUN,Scr in rats with CRF,there were statistically significant differences of Benazepril group and high,medium,low dose of Turbidity-reducing Granule group compared with model group(P0.05).Compared with the model group,the intestinal SIgA of Benazepril group and low,middle,high dose of group increased significantly(P0.05);intestinal SIgA in,middle and high dose group were significantly increased compared with Benazepril group(P0.05).Conclusion Turbidity-reducing Granule could improve renal function and intestinal immune function.
【Fund】: 2013年云南省自然科学基金(2011FZ258)
【CateGory Index】: R285.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 2 Hits
1 HU Yan-wu (Department of Pharmaceutics and Food Science,Tonghua Teachers College,Tonghua,Jilin 134002);Effect of Oplopanax elatus Nakai Stem on the Immune Functions of Immunosuppressed Mice[J];Journal of Anhui Agricultural Sciences;2011-02
2 Zhang Xuexia Miao Mingsan Henan College of Traditional Chinese Medicine,Zhengzhou,Henan China 450008;Intestinal Tract Immunization and Drug Regulation of Organism[J];China Journal of Chinese Medicine;2012-06
Chinese Journal Full-text Database 3 Hits
1 HU Yan-wu* Department of Pharmaceutical and Food Science,Tonghua Normal University,Tonghua,Jilin 134002,China;The effect of RADIX OPLOPANACIS ELATI on Immune Function in Mice with Low Immunity[J];药用植物研究(英文版);2010-12
2 ;Research progress on pharmacological actions of Panax ginseng[J];Ginseng Research;2013-01
3 ZHOU Guangzhen;The Traditional Chinese Medicine Hospital of Mengyin;;Ginseng Treatment Qi deficiency and Desire to Take Off the Profile Syndrome Efficacy Study[J];Journal of Practical Traditional Chinese Internal Medicine;2014-02
【Secondary Citations】
Chinese Journal Full-text Database 9 Hits
1 LIU Bao-jian et al(Academic Affairs Office of Hebei North University,Zhangjiakou,Hebei 075000);Study on the Effects of Total Flavonoids from Trifolium pratense L. on the Immune Function of Mice[J];Journal of Anhui Agricultural Sciences;2009-33
2 WU Ting,YANG Lin-Na,HAN Hai-Yan.Department of Gastroenterology,the First affiliated Hospital of Fu Jian Medical University,Fuzhou(350004),China;Experimental study on the change of intestinal immune function in rats with hyperlipidemia and severe acute pancreatitis[J];International Journal of Digestive Diseases;2009-03
3 Wang Linan1,Wang Qin2,Miao Mingsan1 Henan College of Chinese Medicine,Zhengzhou,Henan,China 450008 Henan Province Hospital of Chinese Medicine,Zhengzhou,Henan,China 450002;Effects of Ficus Carica Polysaccharide on the Immune Function of Immunosuppressive Mice Induced by Cyclophosphamide[J];China Journal of Chinese Medicine;2010-04
4 Wang Yaping, Yu Yong, Yu Yan Liu Wei, Zhang Suxia, Lu Lianrong, Sheng Zhiyong, Shi Zhiguo, Tang Zhongxiong(Burn Research Institute, 304th Hospital of PLA, Beijing 100037);Effect of Zigui granule on intestinal immunobarrier in rat after scald[J];ACADEMIC JOURNAL OF PLA POSTGRADUATE MEDICAL SCHOOL;1998-01
5 YUSUP Abdiryim1,IMAM Guzalnur1,ROZI Nurjan1,AIKEMU Ainiwaer2,UPUR Halmurat1 1. Faculty of Traditional Uighur Medicine,Xinjiang Medical University,Urumqi 830011,China 2. Institute of Pharmacy,Xinjiang Medical University,Urumqi 830011,China;Effects of Immune Regulation of Abnormal Savda Munziq Granular on Immune Suppressed Mice[J];Science & Technology Review;2010-03
6 CHEN Yu-hong1,CHENG Ai-guo2a,ZHANG Xiao-ping2b 1.Department of Orthopedic Surgery,the Fifth Central Hospital of Tianjin, Tianjin 300450,China;2a.Department of Orthopedic Surgery;2b.Department of Anesthesiology, the Affiliated Hospital of Union University of Hebei,Tangshan 063000,China;Protecting action of glutamine on intestinal mucosal damage in complete starved rats[J];Clinical Focus;2011-19
7 Zhang Yunjie,et al.The Affiliated Hospital of Shandong TCM University.Jinan,250011;The Research of Xuebijing Injection on Express of P53 Gene of Immune Cells of Intestinal Wall after Intestinal Ischemia-reperfusion Injury[J];Qingdao Medical Journal;2008-03
8 LIU Xin 1,CHEN Di1,LI Qing-min1,LIU Song-yan2(1.Pharmacy College,Jilin University Changchun 130021,China; 2.Chemistry College,Jilin University Changchun 130021,China);Analysis of Chemical Components Essential Oil in the Root of Oplopanax elatus Nakai[J];Special Wild Economic Animal and Plant Research;2008-02
9 TANG Zhiming1, WANG Haijun2, JIN Qiguan3 (1.School of Sports Science, Nantong University, Nantong 226007, China; 2.Nantong Shipping College, Nantong 226010, China; 3.School of PE, Yangzhou University, Yangzhou 225009, China);Effect of Soybean Peptide Supplementation on the Intestinal Immune Function of Overtraining Rats[J];Journal of Tianjin University of Sport;2009-03
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved