Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chongqing Medicine》 2016-03
Add to Favorite Get Latest Update

The value of thromboelastography in evaluating the risk of bleeding in patients with acute leukemia

Zhao Mei;Chen Shu;Lou Shifeng;Deng Jianchuan;Zhou Kang;Department of Hematology,the Second Affiliated Hospital of Chongqing University;  
Objective To investigate the role of thrombelastography(TEG)in assessing the risk of bleeding and diagnostic value in patients with acute leukemia(AL).Methods The TEG and PLT data were counted in 127patients(272sets of data)who were diagnosed with AL.Those patients were divided into two groups:group 1(including patients with bleeding)and group 2(including patients with no bleeding).The indicators(R values,K values,α-angle,MA values)and PLT count were compared between two groups.Those data with PLT30×10~9/L of these two groups also were divided and the 4indicators of TEG were compared between the two groups.We used the ROC curve to evaluate the sensitivity and specificity in assessing the risk of bleeding.Results According to the data in total,the K value,R value of the group 1were higher than those of the group 2(P0.05);theα-angle and MA value,PLT counts of group 1were lower than those of the group 2(P0.05).In those AL patients whose PLT30×10~9/L,the K value of the group 1was higher than that of the group 2(P0.05);theα-Angle and MA value of the group 1were lower than those of the group 2(P0.05);R values and PLT count were not different between the two groups(P0.05);the areas under the ROC curve about the PLT counts,MA value andα-angle were more than 0.5(0.750,0.740 and 0.653).ConclusionTEG could predict the risk of bleeding in acute leukemia patients and it could be used in clinical application.
【CateGory Index】: R733.71
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved