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《Chongqing Medicine》 2017-08
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The study on the change of serum levels of soL-CXCL16 and NT-proBNP in patients with percutaneous coronary stenting following PCI

Cao Li;An Dongmei;Shi Lei;Zong Gangjun;Department of Cardiology,the 101 Hospital of PLA;Department of Cardiology,The Traditional Chinese Medical Hospital of Jiangsu Province;  
Objective To investigate the clinical value of the variety of serum levels of soL-CXCL16 and NT-proBNP peripercutaneous coronary intervention(PCI)in patients with acute myocardial infarction(AMI).Methods A total of 77 cases received PCI were selected to research group.And the contemporaneous 30 healthy persons were chosen to control group.The serum levels of soL-CXCL16,NT-proBNP and cTnT were detected by ELISA.The relationships of soL-CXCL16 and NT-proBNP to cTnT were detected by Pearson linear correlation analysis.Results Compared to pre-PCI,the serum levels of CXCL16 were rising to the peak point at 0.5hpost-PCI,and were decreasing from 2.0hpost-PCI,then the serum levels of CXCL16 were declining to the levels of pre-PCI at 24.0hpost-PCI(P0.05).And the serum levels of NT-proBNP were rising from 0.5hpost-PCI,and the peak point was at 24.0h post-PCI(P0.05).The postive relationships of the serum levels of CXCL16 and NT-proBNP to the serum levels of cTnT were confirmed by Pearson linear correlation analysis(P0.01).Conclusion Monitoring of soL-CXCL16 and NT-proBNP for patients with percutaneous coronary stenting could provide foundation for prognosis evaluation of PCI.
【Fund】: 国家自然科学基金资助项目(81371657)
【CateGory Index】: R542.22
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