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《Chongqing Medicine》 2017-10
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Value of reactive hyperemia index in predicting postoperative angina pectoris in patients with percutaneous coronary intervention

He Yun;Cheng Xiaofeng;Fan Huaping;Liu Ting;Wang Ke;Jin Jun;Department of Cardiovascular Internal Medicine,Xinqiao Hospital of Third Military Medical University;  
Objective To explore the value of reactive hyperemia index(RHI)in predicting the postoperative angina pectoris(AP)in the patients with percutaneous coronary intervention(PCI).Methods Three hundreds and forty-seven patients with coronary heart disease treated by PCI therapy were continuously enrolled in our department from October 10 2015 to August 10 2016.RHI was detected in all cases during hospitalization period by using the noninvasive endothelial function test(Endo-PAT)technique.Then the cases were divided into the control group(RHI≥1.67)and observation group(RHI1.67)according to RHI results.The incidence of AP after discharge from hospital,rehospitalization rate due to AP,frequency and duration of AP were observed in the two groups.Results The AP incidence rates in the control and observation group were 17.04% and 31.13%respectively,the difference was statistically significant(P=0.003);the re-hospitalization rate due to AP was 2.22% and 7.55% respectively,the difference was statistically significant(P=0.035);the incidence rates of AP attack≥5times were 6.67%and 16.51%respectively(P=0.008);the duration of AP was(6.39±2.68)min and(8.67±2.58)min,respectively(P=0.001);the Logistic regression analysis showed that the Syntax scores≥23points and RHI1.67 were the risk factors for AP recurrence after PCI(OR=2.265,95%CI:1.354-3.787,P=0.002;OR=2.110,95%CI:1.228-3.628,P=0.007).Conclusion Reduced RHI is closely related with recurrent AP after PCI,increases the incidence,rehospitalization rate due to AP,attack frequency and duration of AP.
【Fund】: 国家“十三五”重点研发计划资助项目(2016YFC1301304);; 2015年度医院临床科研项目(2015YLC07);; 2016第三军医大学保健专项课题(16BJZ37)
【CateGory Index】: R541.4
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