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《Chongqing Medicine》 2017-13
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Clinical study on microcirculation resistance index for predicting major adverse cardiac events after PCI operation in patients with ST segment elevation myocardial infarction

Wang Shixiang;Xu Wei;Chen Youquan;Lu Zhifeng;Chen Ximing;Chen Cibin;Department of Cardiology,Third Affiliated Hospital of Guangzhou Medical University;Department of Cardiology,Huadu District People′s Hospital;  
Objective To investigate the clinical value of the index of microcirculation resistance(IMR)in the prediction of major adverse cardiac events after PCI in the patients with ST segment elevation myocardial infarction.Methods Forty-eight inpatients with acute ST segment elevation myocardial infarction(STEMI)in the cardiology department CCU of our hospital from December 2013 to June 2015 were selected,including 38 males and 10 females,and divided into 3groups according to the measured IMR value after PCI operation:the group A,IMR≤25(n=18);group B,IMR 25~32(n=16);group C,IMR≥32(n=14).Serum NT-ProBNP was collected,and the data in cardiac color ultrasound after PCI and at postoperative 1year:left ventricular ejection fraction(LVEF)and left ventricular end diastolic diameter(LVEDD),and major adverse cardiac events within 1years after PCI were also collected.Results The serum of concentrations NT-ProBNP were compared among the three groups[(2 734.83±1 009.40)vs.(4 929.68±611.52)vs.(7 480.64±2 082.78)],and the difference among 3groups was statistically significant(F=35.449,P=0.000).The difference of LVEF among the three groups had statistal significance[(54.00±5.99)vs.(52.31±4.35)vs.(49.29±4.68),F=3.376,P=0.043)],and there was no statistical difference among the three groups in LVEDD(P0.05).The difference of LVEF at postoperative 1year among 3groups had statistical significance[(57.28±5.21)vs.(54.43±3.69)vs.(46.43±5.33),F=16.744,P=0.000],and the difference of LVEDD(48.94±1.95)vs.(50.63±2.68)vs.(52.14±2.69)among3groups was statistically significant(F=6.875,P=0.002).The differences in the major adverse cardiac events,cases of cardiac death and cases of heart failure after postoperative 1year among 3groups were statistically significant(χ~2 value=6.707,P=0.035;χ~2 value=6.084,P=0.048);the occurrence of again ACS,again PCI and malignant arrhythmia had no statistical difference among 3groups(P0.05).Conclusion Measurement of IMR after PCI in the patients with STEMI can effectively predict the heart function and the risk of major adverse cardiac events within 1year.
【Fund】: 广州医科大学青年项目(2013A23)
【CateGory Index】: R542.22
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 WANG Shi-chao;Zhang Chun-quan;LIU Yu-hao;WU Yu;Shao Yi-bing;Xu Wen-liang;Wang Xu;Department of Cardiology, Qingdao Municipal Hospital of Qingdao University Medical College;;Comparisons of index of microcirculatory resistance and heart function of good and bad coronary collateral circulation in ST segment elevation myocardial infarction[J];中国循证心血管医学杂志;2016-02
【Co-citations】
Chinese Journal Full-text Database 3 Hits
1 Wang Shixiang;Xu Wei;Chen Youquan;Lu Zhifeng;Chen Ximing;Chen Cibin;Department of Cardiology,Third Affiliated Hospital of Guangzhou Medical University;Department of Cardiology,Huadu District People′s Hospital;;Clinical study on microcirculation resistance index for predicting major adverse cardiac events after PCI operation in patients with ST segment elevation myocardial infarction[J];重庆医学;2017-13
2 WANG Shi-xiang;XU Wei;CHEN Ximing;CHEN You-quan;CHEN You-quan;Department of Cardiology,The Third Affiliated Hospital of Guangzhou Medical University;Department of Cardiology,People′s Hospital of Huadu District;;Clinical value of coronary artery index of microcirculatory resistance in predicting the rate of re-hospitalization after PCI in patients with STEMI in 1 years[J];岭南心血管病杂志;2017-02
3 JIANG Rong-hu;Department of Cardiology, The First People's Hospital of Yibin;;Predictive value and impact analysis on the index of microcirculatory resistance in patients with coronary artery occlusion after selective percutaneous coronary intervention[J];岭南心血管病杂志;2016-06
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