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《Chongqing Medicine》 2017-13
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Comparison of the efficiency and safety of two different treatments in middle cerebral artery stenosis

Hu Xiaolu;Gao Fei;Chen Kangning;Department of Neurology,Southwest Hospital Affiliated of Third Military Medical University;  
Objective To evaluate the efficacy and safety of percutaneous transluminal angioplasty and stenting of intravascular stenting(PTAS)and internal medicine in the treatment of secondary severe stroke in young patients with severe symptomatic middle cerebral artery stenosis.Methods The clinical data of 77 cases with severe symptomatic middle cerebral artery stenosis(stenosis rate≥70%)confirmed by digital subtraction angiography(DSA)were collected retrospectively in our hospital from January2011 to June 2015.The patients were divided into PTAS group and medical treatment group,and the data were collected including the modified Rankin Score(mRS score)at admission,the US National Institutes of Health Stroke volume neurological impairments score(NIHSS score)at admission,as well as mRS score,the recurrence of ischemic stroke,death and intracerebral hemorrhage within 1year.Results The primary end-point rates within 30 days after enrollment in PTAS group and medical treatment group were 0% and 5.77% respectively,and the stroke recurrence rates within 1year were 4.35% and 13.46% respectively,The difference was not statistically significant(P0.05).Meanwhile,there was no death and intracerebral hemorrhage in both two groups.The rates of mRS≤1were 91.30% and 69.23% respectively in PTAS group and medical treatment group,and the difference was statistically significant(P0.05).The rates of mRS≤2were 95.65% and 84.62%respectively in PTAS group and medical treatment group,and the difference was not statistically significant(P0.05).Conclusion PTAS is safe for the severe symptomatic middle cerebral artery stenosis,and is more efficient in dectasing the risk of recurrent stroke in young population compared with medical treatment.
【CateGory Index】: R743.3
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