Study on colorectal distension with partially automated and individualized insufflation of air for dual-energy CT colonography
Liang Dan;Guo Hongmei;Duan Chaijie;Luo Mingyue;Zhu Dongyun;Qiu Jianping;Wenli Cai;Department of Radiology,Guangzhou First People′s Hospital;Department of Radiology,the Sixth Affiliated Hospital of Sun Yat-sen University;Department of CT and MR,Mongolia Autonomous Prefecture People′s Hospital of Bayinguoleng;Research Center of Biomedical Engineering,Graduate School at Shenzhen,Tsinghua University;Department of Radiology,Massachusetts General Hospital and Harvard Medical School;
Objective To study the compliance of examinees,and effectiveness of colorectal distension with partially automated and individualized insufflation of air for dual-energy CT colonography.Methods Forty-six healthy adult volunteers without history of conditions affecting gastrointestinal motor function were enrolled in this study.One day before CT examination,volunteers were asked to orally administered 60 mL 4% diatrizoate meglumine five times for fecal tagging.Air was insufflated by using an inflator in a partially automated and individualized manner.The volunteers were initially asked to assume the right lateral decubitus position,then slowly turn to the supine position.Insufflation rate began at 1.5L/min,and decreased to 0.5L/min at later stage.The necessity and volume of air insufflation were decided according to effectiveness of colorectal distension on CT scout images,self-reported sensation of volunteers,and intestinal pressure.Dual-energy CT scanning was performed,and dual-energy blended images were acquired.Compliance of volunteers was statistically analyzed.The effectiveness of colorectal segments distension was statistically analyzed by using Kruskal-Wallis H test.Results No abdominal pain,bloating,nausea or vomiting were noted in the 46 volunteers.All volunteers easily accepted colorectal insufflation of air,with grade 1compliance.The effectiveness of colorectal distension of grades 1,2,3and 4were 0%,2.1%,5.1% and 92.8%,respectively.The difference of effectiveness of colorectal segments distension had no statistical significance(χ2=6.19,P=0.288).The effectiveness of insufflation was poor in 6colorectal segments,including 2in sigmoid colon and 2in rectum.Effectiveness of insufflation was suboptimal in 14 colorectal segments,including4 in descending colon,4in sigmoid colon,and 3in rectum.Conclusion Compliance of examinees with partially automated and individualized insufflation of air for dual-energy CT colonography is excellent,with good effectiveness of colorectal distension.
【Fund】： 国家自然科学基金资助项目(81230035);; 广东省科技计划项目(2013B051000016)
【CateGory Index】： R816.5
【CateGory Index】： R816.5