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《Chongqing Medicine》 2017-14
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Observation of clinical effect of glucocorticoid and hyperbaric oxygen therapy on the high-frequency and diminishing sudden deafness

Yang Li;Gan Qiang;Fang Hongyan;Yang Guijun;Department of Otolaryngology Head and Neck Surgery,Chongqing General Hospital;  
Objective To investigate the curative effect of glucocorticoid and hyperbaric oxygen therapy on the high-frequency and diminishing sudden deafness.Methods A total of 260 patients with high-frequency and diminishing sudden deafness were divided into hormone group(n=110),hyperbaric oxygen group(n=80)and routing group(n=70,ginaton 87.5mg+5% GS 250 mL static drops static drops,intramuscular injection of vitamin B1 1.5mg+cobamamide 0.1g and 2%lidocaine 10mL+5% GS 250 mL static drops).The first two groups were added oral prednison and hyperbaric oxygen therapy on the basis of therapy of routing group.The effect of comparison analysis was conducted after 10 days of treatment according to the course of disease which was less than that of or equal to 7days or greater than 7days.Results The overall curative effect of hormone group and hyperbaric oxygen group was better than that of routing group,and the difference was statistically significant(P0.05).During the whole course of disease,the difference of therapeutic effect between routing group and the other two groups was statistically significant(P0.05).Conclusion The glucocorticoid and hyperbaric oxygen therapy both have really curative effect on high-frequency and diminishing sudden deafness.
【Fund】: 重庆市科委社会民生科技创新专项(cstc2015shnszx120060);; 重庆市卫计委2015年医学科研项目(2015MSXM068)
【CateGory Index】: R764.4
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1 ZHANG Shu'e;;Therapeutic effect of combined hyperbaric oxygen and intratympanic injection of methylprednisolone on sudden sensorineural hearing loss[J];职业卫生与应急救援;2017-03
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