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《Chongqing Medicine》 2017-14
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Study on the relationship between serum oxytocin levels and social competence in children with autism

Zheng Peiyu;Shao Zhi;Zhang Yaru;He Xiongwei;Child Autism Rehabilitation Center,Chongqing Ninth People′s Hospital;Medicament Department,Chongqing Ninth People′s Hospital;Pharmaceutical Research Laboratory,Chongqing Ninth People′s Hospital;  
Objective To explore the difference of serum oxytocin levels between autistic children and healthy children at the age of 3-5,and the relationship between serum oxytocin levels and social competence in children with autism.Methods Twentyfive autistic children and twenty healthy children were tested by an enzyme-linked immunosorbent assay to evaluate the oxytocin levels;the SRS was used to evaluate social competence of children with autism.Results Mann-Whitney test showed there were significantly differences in oxytocin level between autistic children and healthy children(P0.05).The social competence of autistic children was negatively correlated to oxytocin levels(r=-0.735,P0.01).Multiple liner regression analyses showed that oxytocin level was an impact factor of the social competence of autistic children(F=11.931,P0.01).Conclusion This study indicates that the serum oxytocin level maybe a factor which influence the social competence of autistic children.
【Fund】: 重庆市医学科研项目(20143047)
【CateGory Index】: R749.94
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【Citations】
Chinese Journal Full-text Database 3 Hits
1 XU Xin-Jie,ZHANG Rong Neuroscience Research Institute,Peking University;Department of Neurobiology,Peking University Health Science Center;Key Laboratory for Neuroscience of the Ministry of Education,China;Key Laboratory for Neuroscience of the Ministry of Health,Beijing 100191,China;Role of sex differences in pathogenesis of autism:A review[J];中国心理卫生杂志;2012-06
2 ZHANG Rong,XU Xin-Jie,HAN Ji-Sheng Neuroscience Research Institute,Peking University,Beijing 100191,China;Role and therapeutic potential of oxytocin in autistic patients' social impairments(Review)[J];中国心理卫生杂志;2011-06
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【Co-citations】
Chinese Journal Full-text Database 6 Hits
1 Zheng Peiyu;Shao Zhi;Zhang Yaru;He Xiongwei;Child Autism Rehabilitation Center,Chongqing Ninth People′s Hospital;Medicament Department,Chongqing Ninth People′s Hospital;Pharmaceutical Research Laboratory,Chongqing Ninth People′s Hospital;;Study on the relationship between serum oxytocin levels and social competence in children with autism[J];重庆医学;2017-14
2 DING Ying;LI Yanfang;ZOU Yuchen;School of Brain and Cognitive Sciences, National Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University;National Innovation Center for Assessment of Basic Education Quality;;Brain Development of Children with Neurocognitive Developmental Disorders and Implications for Intervention[J];心理科学进展;2015-08
3 LIANG Xiao-hua;Ministry of Education Key Laboratory of Child Development and Disorders,Chongqing University of Medical Science;;Research the Treatment and Social Security Status of Autism in Chongqing[J];中国卫生事业管理;2015-02
4 ZHANG Ying;XU Xiu;Department of Child Health Care,Children's Hospital of Fudan University;;Associations of nonapeptide with social behavior and autism[J];教育生物学杂志;2013-04
5 MA Yao,YI Ming-ji,LI Yin,FU Wei-wei, WAN Jin-e.Department of Child Health Care,The Affiliated Hospital of Medical College,Qingdao University,Qingdao 266003,China;Effects of normobaric hyperoxia on the learning and memory abilities of valproic acid autism model rats and the morphology of pyramidal cells in hippocampal CA1 region[J];中华行为医学与脑科学杂志;2012-12
6 XU Xin-Jie,ZHANG Rong Neuroscience Research Institute,Peking University;Department of Neurobiology,Peking University Health Science Center;Key Laboratory for Neuroscience of the Ministry of Education,China;Key Laboratory for Neuroscience of the Ministry of Health,Beijing 100191,China;Role of sex differences in pathogenesis of autism:A review[J];中国心理卫生杂志;2012-06
【Secondary Citations】
Chinese Journal Full-text Database 4 Hits
1 ZHANG Rong,XU Xin-Jie,HAN Ji-Sheng Neuroscience Research Institute,Peking University,Beijing 100191,China;Role and therapeutic potential of oxytocin in autistic patients' social impairments(Review)[J];中国心理卫生杂志;2011-06
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