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《Chongqing Medicine》 2017-15
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Clinical value of amplitude integrated EEG in early diagnosis and prognosis of neonatal asphyxia

Ma Juan;Chen Long;Xue Ying;Tang Shifang;Zhao Jinning;Shi Yuan;Department of Pediatrics,Daping Hospital,Research Institute of Surgery,Third Military Medical University;  
Objective To investigate the clinical value of amplitude integrated electroencephalogram on early diagnosis and prognosis evaluation of brain injury caused by neonatal asphyxia.Methods A total of 34full-term asphyxiated neonates(asphyxia group)hospitalized in NICU of our hospital from January 2015 to September 2015 were selected;meanwhile,34full-term healthy infants(control group)of the same term were selected.All cases were monitored for the activities of aEEG background,sleep-awakening cycle(SWC)and epileptic activity(SA)within 6hours after birth.Meanwhile,the relationships between various indexes and asphyxia degree and brain injury were analyzed.Results The electroencephalogram of the asphyxia group was 52.9% and the rate of SWC was 58.8%,which were lower than those of the control group,and the difference had statistic significance(P0.05).Meanwhile,neonates with epileptic activity in asphyxia group accounted for 11.8%,which was higher than that of control group significantly(P0.05).Conclusion The AEEG changes of neonates at early period after birth are closely related to perinatal asphyxia and brain injury after asphyxia.The application of amplitude integrated electroencephalogram has an important significance on early diagnosis of neonatal asphyxia.
【Fund】: 国家自然科学基金资助项目(81100458)
【CateGory Index】: R722.12
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