Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chongqing Medicine》 2017-16
Add to Favorite Get Latest Update

Risk assessment of cardiovascular and other target organs damage in patients with type 2 diabetes and different body mass indexes

Yang Hongwei;Zhang Youyou;Wang Lijun;Department of Endocrinology,Taizhou Municipal First People′s Hospital;  
Objective To investigate the risk of cardiovascular and other target organs damage in the patients with type 2diabetes mellitus(T2DM)and different body mass indexes(BMI).Methods One hundred and twenty-six patients with T2 DM admitted to our hospital from January 2014 to January 2016 were prospectively collected,including 57 cases in the study group(BMI≥25kg/m2)and 69 cases in the control group(18.5kg/m2≤BMI25kg/m2).The clinical features of the two groups were analyzed,and the correlation between BMI and related indexes of target organ damage[carotid artery intima media thickness(IMT),arterial stiffness index,coronary heart disease index and glomerular filtration rate]were analyzed.Results There was no statistically significant difference in fasting blood glucose between the two groups(P=0.953),BMI in the study group was significantly higher than that in the control group(P=0.000).When compared with the control group,the study group showed a significantly increase in age(P=0.038);a significant increase in systolic blood pressure(P=0.000);a significantly increase in diabetic family history(P=0.000);a significant increase in total cholesterol(P=0.012);a significant increase in triglycerides(P=0.000);a significant decrease in high density lipoprotein(P=0.003);a significant increase in HOMA-IR level(P=0.000);a significant decrease in HOMA-βlevel(P=0.000);a significant increase in IMT level(P=0.000);a significant increase in arterial stiffness index(P=0.000);a significant increase in coronary heart disease index(P=0.001);and a significant decrease in glomerular filtration rate(P=0.000).The Pearson linear correlation analysis showed that BMI was correlated with IMT,atherosclerosis index,coronary heart disease index and glomerular filtration rate,the r values were 0.234,0.257,0.294 and 0.211respectively(all P=0.000).Conclusion The BMI level in the patients with T2 DM is related to cardiovascular and renal function damage.
【CateGory Index】: R587.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved