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《Chongqing Medicine》 2017-26
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Study on diagnostic value of procalcitonin and T cell subsets in infection after acute cerebral infarction

Ma Lina;Li Xing;Yu Dan;Wang Liang;Zhou Zhiping;Department of Neurology,Haikou Municipal People′s Hospital;Department of Oncology and Chemotherapy,Haikou Municipal People′s Hospital;  
Objective To study the diagnostic value of procalcitonin and T cell subsets in infection after acute cerebral infarction(ACI).Methods One hundred and twenty-two patients with ACI in our hospital from February 2015 to January 2016 were selected and divided into the infection group(60cases)and non-infection group(62cases)according to whether infection occurring.The systolic blood pressure,diastolic blood pressure,body temperature,NIHSS score,cerebral infarction location,procalcitonin,CD4 level,CD8level were compared between the two groups.The Logistic regression analysis was performed.Results The NIHSS score in the infection group was(14.9±5.7)points,which was significantly higher than(10.6±3.8)points in the non-infection group,the differences were statistically significant(P0.05).The number of pons infarction in the infection group accounted for35.48%(22/60),which was significantly higher than 17.74%(11/62)in the non-infection group,the differences were statistically significant(P0.05).The procalcitoninl level in the infection group was significantly higher than that in the non-infection group,while the levels of CD4 and CD8were significantly lower than those in the non-infection group,the differences were statistically significant(P0.05).The multivariate Logistic regression analysis showed that the risk factors affecting infection after cerebral infarction included pons infarction,NIHSS score,procalcitonin,CD4 and CD8levels.Conclusion Detecting procalcitonin and T cell subsets in the patients with ACI in clinical work is conducive to predict the infection occurrence.
【CateGory Index】: R743.33
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