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《Chongqing Medicine》 2017-26
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Clinical application of remifentanil in painless bronchoscopic examination of elderly patients

Liao Xingzhi;Quan Yaochen;Li Guowei;Liu Yufang;Zhou Maitao;Department of Anesthesiology,101 Hospital of PLA;  
Objective To investigate the effects of remifentanil in painless bronchoscopic examination of elderly patients.Methods One hundred and twenty elderly patients undergoing painless bronchoscopic examination were randomly divided into 4groups(n=30),the group A was administered with propofol and the groups B,C and D were administered with propofol and remifentanil(remifentanil dose:0.05μg·kg~(-1)·min~(-1) in the group B,0.10μg·kg~(-1)·min~(-1) in the group C and 0.15μg·kg~(-1)·min~(-1)in the group D).The body moving response,hemodynamic changes,propofol dose,examination time,wake-up time,departure time and adverse reactions in each group were observed during the examination process.Results During the examination process,the body moving response and bucking of the group A were significantly higher than those of the other three groups(P0.05);in hemodynamics,the group A fluctuated greatly,while the group B,C and D were relatively stable,but the incidence rate of hypotension,bradycardia and transient respiratory depression of the group D were higher than those of the other three groups(P0.05);propofol dose of the group A was significantly higher than that of the other three groups(P0.05)and the group B was higher than the group C and D(P0.05).In wake-up time and departure time,the groups B,C,D were significantly better than the group A(P0.05),while the group C and D were better than the group B(P0.05).Conclusion Remifentanil can be used in painless bronchoscopic examination for elderly patients,and the effect is better by using propofol combined with remifentanil at a dose of 0.1μg·kg~(-1)·min~(-1).
【CateGory Index】: R614
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