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《Infectious Disease Information》 2017-06
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Clinical features of AIDS patients with Nontuberculous mycobacteria infection

WANG Fang;GUO Jing-jing;XIANG Pan;GAO Gui-ju;YANG Di;HAN Ning;XIAO Jiang;NI Liang;LIANG Hong-yuan;ZHANG Fu-jie;Department of Infectious Diseases,Beijing Ditan Hospital,Capital Medical University;  
Objective To discuss the clinical features of AIDS patients with Nontuberculous mycobacteria(NTM) infection.Methods Clinical manifestations,locations,immune statues etc.of 33 AIDS patients with NTM were analyzed,and were compared with those infected with Mycobacterium tuberculosis(MTB).Results Among 33 NTM infected patients,the median of CD4 count was 18/μL.The hemoglobin was(93.8±22.9) g/L,anemia was found in 29 patients(87.9%).The monocyte percentage was(8.66±5.08)%,rose in 16 patients(48.5%).The level of albumin was(32.7±5.2) g/L,declined in 31 patients(93.9%).Eighteen patients(54.5%) were diagnosed with disseminated NTM disease.Twenty-four patients(72.7%) presented with lesions in lung predominantly.CT showed diffuse nodules or exudative lesions or consolation.No significantly statistic differences were found between NTM and MTB infected patients in clinical,laboratory features.Conclusions Infection of NTM is an AIDS defined illness secondary to advanced immunosuppression in patients with AIDS.Both anemia and hypoproteinemia are common complications.Clinical features of NTM are not easily distinguished from MTB.
【Fund】: 北京市卫生系统高层次卫生技术人才培养计划(2015-3-105)
【CateGory Index】: R512.91
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