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《Infectious Disease Information》 2017-06
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Investigations on blood calcium, phosphorus, intact parathyroid hormone level in 61 HIV/AIDS patients after chronic kidney disease maintenance hemodialysis

LAN Ling-xian;SU Chun-xiong;CHEN Wan;CHEN Qiu-xia;HUANG Rui-fen;ZHENG Hui;LIANG Gang;Department of Blood Purification,The Fourth People's Hospital of Nanning,Guangxi AIDS Clinical Treatment Center;  
Objective To investigate the mineral metabolism disorder and possible influencing factors in HIV/AIDS patients with maintenance hemodialysis(MHD) in Guangxi area.Methods Sixty-one HIV/AIDS patients treated with MHD for more than 3 months in the Fourth People's Hospital of Nanning(Guangxi AIDS Clinical Treatment Center) from 2011 to 2016 were enrolled in this study,and as the observation group,divided into 2 groups:highly active antiretroviral therapy(HAART) group(n=51) and non-HAART group(n=10 cases).In addition,30 non-HIV/AIDS patients treated with MHD for more than 3 months were selected as control group.The mineral metabolism indexes including blood calcium,phosphorus and intact varathvroid hormone(i PTH) were determined.Then the related influencing factors were explored.Results Among the 61 HIV/AIDS patients,the control rate of blood calcium,serum phosphorus and i PTH was 47.54%(29/61),24.59%(15/61) and 21.31%(13/61),respectively.Compared with the control group,the level of blood calcium,phosphorus,i PTH,haemoglobin and ALB levels in the HIV group were significantly lower(P0.05).However,the levels of serum calcium and i PTH in the HAART group were higher than that in non-HAART group.Serum phosphorus in the HAART group were lower than that in non-HAART group(P0.05).Conclusions HIV/AIDS patients in Guangxi area undergoing MHD treatment exhibit unique clinical manifestations of abnormal mineral metabolism.The way of hemodialysis,HAART treatment program and its impact factor need further study.
【Fund】: 南宁市重大科技专项(20163013);; 广西壮族自治区卫生厅自筹经费科研课题(Z2014476)
【CateGory Index】: R512.91;R692
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