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《Infectious Disease Information》 2017-06
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Analysis of mycoplasma infection in 370 female patients with secondary infertility

HUANG You-yuan;WANG Li-zhi;HUANG Xiao-yan;ZHUO Hui-yan;LIAO Yang;SUN Zhao-hui;LI Lin-hai;Department of Laboratory Medicine,Guangzhou General Hospital of PLA;  
Objective To analyze the role of mycoplasma infection in female patients with secondary infertility,and provide reference for clinical diagnosis and treatment.Methods By using retrospective analysis,370 female patients with secondary infertility were selected from Reproductive Center of General Hospital of Guangzhou Military Command of PLA,as infertility group,while 300 natural pregnant women served as the control group.Gynecological examination data,results of Ureaplasma urealyticum(Uu) and Mycoplasma hominis(Mh) infection were collected and analyzed statistically.Results The incidence of tubal obstruction,pelvic adhesion,endometrial lesions and abortion were significantly higher in the infertility group than those in the control group(P 0.05).The positive rates of Uu and Mh were 57.8% and 7.6% in the infertility group,which were significantly higher than those in the control group(20.0%,1.7%)(P 0.05).There were 206 cases(55.7%) with single infection and 18 cases(4.9%) with mixed infection in the infertility group.The incidence of fallopian tubal blockage,endometrial lesions,pelvic adhesion and abortion history in infertile patients with mycoplasma infection were significantly higher than those in uninfected patients(P 0.05).Conclusions Secondary infertility patients have a high prevalence of mycoplasma,and mycoplasma infected patients are associated with an increased incidence of pelvic fallopian tube lesions,suggesting that mycoplasma infection is a possible key factors leading to secondary infertility.Women of childbearing age should strengthen mycoplasma screening and treatment.
【Fund】: 广州市产学研协同创新重大专项(201604040003)
【CateGory Index】: R711.6
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