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《Computerized Tomography Theory and Applications》 2018-03
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The Application Study of Different BSA Normalization Methods in the Evaluation of GFR by Gate's in Elder Patients

YUAN Lei-lei;LIU Jun;WANG Yao;SU Wei-hong;YANG Ji-gang;Department of Nuclear Medicine, Beijing Friendship Hospital,Capital Medical University;  
Objective: To compare the application value of different BSA normalization methods in the evaluation of GFR by Gate's in elder patients. Methods: The clinical data of 91 cases of patients who performed double plasma clearance method(t GFR0) and renography examination(g GFR0) were selected in our study. According to different formulas(Du Bois formula, Gehan and Georgeformula, Stevensonformula, Hu Yongmei formula, Hu Yongmei-gender correction formula), the GFR1-5 were calculated. The correlation of t GFRx and g GFRx were analyzed. The patients were divided into two subgroups according to BMI( group a and group b), and g GFR were recorded as g GFRx-a and g GFRx-b and its correlation with t GFRx-a or t GFRx-b were analyzed. Results: The correlation of t GFR and g GFR was good in whole study cohort, and r5-a= 0.841, which was highest among all paired groups(P 0.05). The correlation of t GFR and g GFR in group b was worse(P 0.05). Conclusion: The evaluation of GFR by Gate's method is well correlated with t GFR, but it is still a difficult clinical question for the GFR evaluation of fat patients, which needs a large sample size of validation.
【Fund】: 国家自然科学基金(81601519);; 北京市医院管理局“青苗”计划专项(QML20170106);; 北京市属医院科研培育计划(PX2017035)
【CateGory Index】: R692;R811
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