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Sun Yuanxia; Yan Yulin;Zhang Yeng;Du Cangjie; Guo Rongcang (Northeast Agricultural University, Harbin 150030,PRC)  
In order to study the mutagenic effects of combined exposure and single exposure to selenium and mercuric chloride, we examined the frequency of micronucleated PCE in the bone marrow of mice and rats.The results indicated that selenium and mercuric chloride both caused the increase in micronucleus frequency in the bone marrow of mice and rats.The differences between the treated and the controls as statistically significant (P0.01). The results obtained also showed that both selenium and selenium-containing soybean can apparently decrease the micronuleus frequency induced by mercuric chloride.This demonstrated that selenium and mercuric chloride had the mutagenic effect when they were used alone, and selenium was effective in inactivating the mutagenicity of mercuric chloride when selenium or selenium-containing soybean were used together with mercuric chloride.
【CateGory Index】: Q2-33
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