Anti-hyperglycemic and Anti-aging Effects of Deer Antler Velvet Extract on Diabetic Mice Induced by Alloxan
Liu Yu,Wang Zhenyu,Zhou Liping(School of Forestry,Northeast Forestry University,Harbin 150040,P. R. China)
An experiment was conducted to study the anti-hyperglycemic and anti-aging effects of deer antler velvet extract on diabetic mice by establishing a mouse model of diabetes induced by alloxan. The alloxan-induced diabetic mice were randomly divided into three dose groups and fed intragastrically with different doses of deer antler velvet extract (1.6,3.2,or 4.8mg/g) for four weeks. Serum glucose level,contents of MDA,glycogen and SOD,and activities of GSH-PX and CAT were determined. Compared with the model control group,deer antler velvet extract could reduce serum glucose and MDA content significantly,increase the contents of glycogen,SOD,GSH-PX and CAT obviously,and enhance the antioxidant ability of ALX-induced diabetic mice. Deer antler velvet extract can effectively control serum glucose level and improve body’s anti-aging ability.