Vitamin D intake in young children with acute lower respiratory infection
Karen S Leis1,J Dayre McNally2,Matthew R Montgomery3,Koravangattu Sankaran1,Chandima Karunanayake4,Alan M Rosenberg1.(1.Department of Pediatrics,University of Saskatchewan,Saskatoon,Saskatchewan; 2.Department of Pediatrics,University of Ottawa,Ottawa,Ontario; 3.Department of Pediatrics,University of Alberta,Edmonton,Alberta; 4.Canadian Centre for Health and Safety in Agriculture,University of Saskatchewan,Saskatoon,Saskatchewan)
Objective To determine if vitamin D intake is associated with acute lower respiratory infections(ALRI) in children.Methods The vitamin D intakes of children younger than 5 years of age admitted to hospital with either bronchiolitis or pneumonia were compared to an unmatched control group of the same age without respiratory infection.Caregivers of 197 children completed a questionnaire collecting information on demographic variables,ALRI risk factors and diet.Associations of ALRI with vitamin D intake and other ALRI risk factors were determined.Results The mean vitamin D intake of children with ALRI was 48 IU/kg/d compared to 60 IU/kg/d in the control group.When controlling for age,ethnicity,socio-economic status,northern residence,breastfeeding,immunizations and smoking contact,children with a vitamin D intake of less than 80 IU/kg/d were greater than 4 times more likely to have ALRI compared to children with a vitamin D intake exceeding 80 IU/kg/d(OR=4.9;95%CI: 1.5~16.4).Conclusions A higher vitamin D intake than currently recommended might be needed to offer protection against diseases such as ALRI.Increased vitamin D supplementation could have important public health consequences,as bronchiolitis and pneumonia are the most common reasons for hospitalization in young children.
【CateGory Index】： R725.6