Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Contemporary Pediatrics》 2019-11
Add to Favorite Get Latest Update

Risk factors for poor prognosis of neonatal bacterial meningitis

LIU Meng-Di;XU Fa-Lin;DUAN Wen-Li;LIU Jia-Xin;LI Xiao-Nan;LIU Ya-Xuan;WANG Yin-Juan;Department of Neonatology, Third Affiliated Hospital of Zhengzhou University;  
Objective To investigate the risk factors for poor prognosis of neonatal bacterial meningitis. Methods A retrospective analysis was performed for the clinical data of 152 children with neonatal bacterial meningitis. According to their prognosis, they were divided into a good prognosis group with 122 children and a poor prognosis group with 30 children. The two groups were compared in terms of general status, initial symptoms, and laboratory findings, and the risk factors for poor prognosis were analyzed. Results Compared with the good prognosis group, the poor prognosis group had a significantly higher proportion of children with a very low birth weight, a peripheral blood white blood cell count(WBC) of 5×10~9/L or 20×10~9/L, a C-reactive protein level of 50 mg/L, a cerebrospinal fluid(CSF) WBC of 500×10~6/L, a CSF glucose level of 1 mmol/L, or a CSF protein level of 2 g/L, as well as significantly higher positive rates of blood culture and/or CSF culture, Gram-positive bacteria, and Streptococcus agalactiae(P0.05). The multivariate logistic regression analysis showed that a CSF glucose level of 1 mmol/L and a CSF protein level of 2 g/L were independent risk factors for poor prognosis of neonatal bacterial meningitis. Conclusions A CSF glucose level of 1 mmol/L and a CSF protein level of 2 g/L are risk factors for poor prognosis of neonatal bacterial meningitis.[Chin J Contemp Pediatr, 2019, 21(11): 1064-1068]
【CateGory Index】: R742.9
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 5 Hits
1 Collaborative Study Group for Neonatal Bacterial Meningitis;;A multicenter epidemiological study of neonatal bacterial meningitis in parts of South China[J];中华儿科杂志;2018-06
2 Li Shan;Wang Ying;Neonatal Intensive Care Unit,Pediatric Department,the First Hospital of Peking University;;The update of diagnosis and treatment of neonatal bacterial meningitis[J];中国小儿急救医学;2017-05
3 Li Shujuan;Qiao Zhongwei;Jiang Siyuan;Yang Mingshu;Cheng Guoqiang;Zhou Qi;Cao Yun;Department of Neonatology,Children's Hospital of Fudan University;Department of Radiology,Children's Hospital of Fudan University;;Clinical and imaging characteristics in neonatal refractory purulent meningitis[J];中华围产医学杂志;2016-05
4 Zha Ping;Wang Lili;Liu Guanghui;Dept of Neonatology,The First Affiliated Hospital of Anhui Medical University;Dept of Neonatology,Anhui Province Children's Hospital;;Analysis of risk factors on poor prognosis of purulent meningitis in neonates[J];安徽医科大学学报;2015-07
5 Zhu Minli;Zhu Jianghu;Li Haijing;Liu Peining;Lin Zhenlang;Department of Neonatology,Yuying Children's Hospital of Wenzhou Medical University;;Clinical analysis and follow-up of neonatal purulent meningitis caused by group B streptococcus[J];中华儿科杂志;2014-02
【Co-citations】
Chinese Journal Full-text Database 9 Hits
1 Du Lizhong;Department of Neonatology,Children's Hospital,Zhejiang University School of Medicine;;Challenges in diagnosis and prevention of neonatal sepsis[J];中华儿科杂志;2019-04
2 Collaborative Study Group for Neonatal Bacterial Meningitis;;A multicenter epidemiological study of neonatal bacterial meningitis in parts of South China[J];中华儿科杂志;2018-06
3 Zhao Cui;Zhang Lan;Cheng Guoqiang;Department of Neonatology,Children's Hospital of Fudan University;;Clinical features of neonatal purulent meningitis caused by different pathogens[J];中华新生儿科杂志;2018-03
4 Hua Chunzhen;Yu Hui;Zhuang Jieqiu;Li Xiaolu;Xu Hongmei;Luo Qiaoer;Lu Hongping;Yu Huimin;Cao Yun;Chen Yiping;Zhang Ting;Jing Chunmei;Du Lizhong;Wang Chuanqing;Lin Zhenlang;Zhang Hong;Chen Xuejun;Hua Ziyu;Division of Infectious Disease,Children's Hospital,Zhejiang University School of Medicine;Division of Infectious Disease,Children's Hospital,Fudan University;Division of Neonatology,Children's Hospital,Zhejiang University School of Medicine;Division of Laboratory Medicine,Children's Hospital,Fudan University;;An analysis of 181 cases with blood stream infection caused by Streptococcus agalactiae in children from 2011 to 2015:a multi-center retrospective study[J];中华儿科杂志;2016-08
5 Li Shujuan;Qiao Zhongwei;Jiang Siyuan;Yang Mingshu;Cheng Guoqiang;Zhou Qi;Cao Yun;Department of Neonatology,Children's Hospital of Fudan University;Department of Radiology,Children's Hospital of Fudan University;;Clinical and imaging characteristics in neonatal refractory purulent meningitis[J];中华围产医学杂志;2016-05
6 YANG Li;ZHANG Ning;ZHANG Jiao;HU Ming;Department of Clinical Laboratory,Women and Children's Hospital of Qingdao;;DETECTION OF GROUP B STREPTOCOCCAL INFECTION IN PREGNANT WOMEN WITH PREMATURE RUPTURE OF MEMBRANE USING COLLOIDAL GOLD METHOD[J];齐鲁医学杂志;2015-06
7 ZHANG Sheng;LUO Xu-feng;ZHOU Tao;Department of Pediatrics,Boai Hospital of Zhongshan,Southern Medical University;;Clinical Features and Therapeutic Strategies of Late-onset Streptococcus Agalactiae Meningitis[J];中国全科医学;2015-29
8 Zhao Ning;Wang Ping;Wei Mou;Lu Weineng;He Juan;Gu Rui;Jiang Cuichan;Department of NICU,Guangzhou Women and Children's Medical Center;;Clinical analysis of neonatal purulent meningitis caused by group B streptococcus[J];中国小儿急救医学;2015-03
9 DONG Ya;XU Yin-Quan;LIN Zhen-Lang;Department of Neonatology, Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University;;Clinical analysis of 101 cases of neonatal intestinal perforation[J];中国当代儿科杂志;2015-02
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Li Shan;Wang Ying;Neonatal Intensive Care Unit,Pediatric Department,the First Hospital of Peking University;;The update of diagnosis and treatment of neonatal bacterial meningitis[J];中国小儿急救医学;2017-05
2 Liu Shuhua;Liu Cuiqing;Ma Li;Zhang Shuying;Yang Juan;Department of Neonatology,Children's Hospital of Hebei Province;;Characteristics of cerebrospinal fluid in neonatal purulent meningitis[J];中国小儿急救医学;2015-07
3 The Collaborative Group for Neonatal Meningitis Study;;Epidemiology of neonatal purulent meningitis in Hebei Province, China: a multicenter study[J];中国当代儿科杂志;2015-05
4 YANG Ming-shu;WANG Li;ZHAI Qian;PA Mi-er;ZHOU Jian;CAO Yun;QIAO Zhong-wei;Department of Radiology,Children's Hospital of Fudan University;Department of Neonatology,Children's Hospital of Fudan University;;Predicting the outcomes at discharge of neonatal bacterial meningitis : a semi-quantitative MRI-based-score system analysis[J];中国循证儿科杂志;2015-02
5 Zhu Minli;Hu Qianhong;Mai Jingyun;Lin Zhenlang;Department of Neonatology,Second Affiliated Hospital&Yuying Children's Hospital of Wenzhou Medical University;;Analysis of pathogenic bacteria and drug resistance in neonatal purulent meningitis[J];中华儿科杂志;2015-01
6 Zhu Minli;Zhu Jianghu;Li Haijing;Liu Peining;Lin Zhenlang;Department of Neonatology,Yuying Children's Hospital of Wenzhou Medical University;;Clinical analysis and follow-up of neonatal purulent meningitis caused by group B streptococcus[J];中华儿科杂志;2014-02
7 LIN Ying-rong;JIANG Jin-biao;LUO Ling-ling;PAN Dan-feng;The First People′s Hospital of Wenling;;Clinical value of serum procalcitonin in identifying pathogenic bacteria causing meningitis in children[J];中华医院感染学杂志;2014-02
8 ;新生儿B族链球菌败血症20例临床分析[J];当代医学;2012-16
9 LIU Gang,ZHANG Er-qing,CHEN He-ying,LI Shao-ying,CHI Wei,JIANG Zai-fang(Beijing Children's Hospital,Affiliated to Capital Medical University,Beijing 100045,China);Risk factors for an adverse outcome of childhood bacterial meningitis[J];临床儿科杂志;2011-02
10 ZHU Min-li ZHENG Ge CHEN Jin-ni LIN Zhen-lang ZHU Jiang-hu LIN Jin.Department of Neonatology,Yuying Children's Hospital of Wenzhou Medical College,Wenzhou 325000,China;Comparative analysis of the pathogens responsible for hospital acquired and community acquired late onset neonatal septicemia[J];中华儿科杂志;2008-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved