Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Contemporary Pediatrics》 2019-11
Add to Favorite Get Latest Update

Long-term prognosis of vesicoureteral reflux: a follow-up observation of 138 children

LIN Hong-Zhou;ZHU Qi-Fan;YANG Qing;ZHUANG Jie-Qiu;Department of Pediatric Nephrology, Second Affiliated Hospital &Yuying Children's Hospital of Wenzhou Medical University;  
Objective To study the long-term prognosis of vesicoureteral reflux in children. Methods A retrospective analysis was performed for the clinical data of 138 children(218 ureters with reflux) who were diagnosed with vesicoureteral reflux for the first time from November 2005 to March 2017 and received medical treatment and regular follow-up. According to the initial grade of reflux, the ureters with reflux were divided into a low-grade group(141 ureters, grade I-III) and a high-grade group(77 ureters, grade IV-V), and the two groups were compared in terms of clinical data and follow-up results. Results Among the 138 children, there were 82 boys and 56 girls. Their age ranged from 31 days to 10 years at the time of confirmed diagnosis, with a median age of 8 months. The follow-up time ranged from 8 months to 7 years, with a median follow-up time of 1.4 years. At the time of confirmed diagnosis, the high-grade group had significantly higher levels of urinary N-acetyl-β-D-glucosaminidase, urinary microalbumin and urinary immunoglobulin G than the low-grade group(P0.05). Among the 218 ureters with reflux, 132(60.6%) achieved a reduction in the grade of reflux(among which 74 achieved complete disappearance of reflux), 43 had no change in the grade of reflux, and 43 had an increase in the grade of reflux. Compared with the high-grade group, the low-grade group had a significantly higher complete remission rate(41.1% vs 19.5%, P=0.001) and a significantly shorter time to complete remission of reflux(P=0.002). Conclusions Most children with vesicoureteral reflux can achieve a reduction in the grade of reflux or even complete disappearance of reflux during follow-up, and the children with low-grade reflux have better prognosis than those with high-grade reflux. [Chin J Contemp Pediatr, 2019, 21(11): 1069-1072]
【CateGory Index】: R726.9
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 3 Hits
1 JI Li-na,CAO Li,CHEN Da-kun,CUI Yan-chun,ZHANG Yu-lin,YE Hui,HAO Chun-sheng,YUAN Xin-yu. Department of Nephrology,Children's Hospital Affiliated to Capital Institute of Pediatrics,Beijing 100020,China;Evaluation of the clinical and imaging examination in high-risk children with vesicoureteral reflux[J];中华儿科杂志;2011-04
2 Shanghai Pediatric Nephrology Association and Shanghai Pediatric Urology Association;Consensus of experts on the diagnosis and management of urinary tract infection and vesicoureteric reflux in children(2007 Shanghai)[J];临床儿科杂志;2008-04
3 SHI Xiao-na~*,ZHANG Bi-li. *Graduate School,Tianjin Medical University,Tianjin 300070,China;Significance of joint detection of serum cystatin C,procalcitonin,and urine N-acetyl-β-D-glucosaminidase combined detection on localization diagnosis of the urinary tract infection in children[J];中华实用儿科临床杂志;2013-05
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 The Subspecialty Group of Renal Diseases,the Society of Pediatrics,Chinese Medical Association;;Evidence-based guideline on diagnosis and treatment of urinary tract infection (2016)[J];中华儿科杂志;2017-12
2 Meng Zhe;Liu Xingnian;Department of Urology,Zhongnan Hospital of Wuhan University;;Diagnostic value of serum procalcitonin and C-reactive protein in children with urinary tract infection[J];国际泌尿系统杂志;2017-06
3 Zhang Hongying;Wu Yubin;Pediatric Department,Shengjing Hospital of China Medical University;;Advances in diagnosis and treatment of urinary tract infection in children[J];国际儿科学杂志;2016-07
4 Hou Ling;Du Yue;Wu Yubin;Zhao Chengguang;Tang Ying;Wang Xiuli;Department of Pediatrics,Shengjing Hospital of China Medical University;;Bacterial uropathogens isolate and causes analyse in children with urinary tract infection under 5 years of age[J];中国小儿急救医学;2015-12
5 ZHANG Lin;ZHAO Li-ping;ZHOU Hong-xia;GE Ting-ting;Department of Nephrology and Rheumatism,Childrerls Hospital;;Clinical analysis of 42 cases of vesicoureteric reflux in children[J];临床肾脏病杂志;2015-11
6 Zhang Tao;Shen Qian;Xu Hong;Department of Nephrology and Rheumatology,the Children's Hospital Affliated to Fudan University;;Progress of the vesicowreteral reflux imaging diagnosis[J];国际儿科学杂志;2015-06
7 YANG Jiao-feng;WANG Wei-juan;KANG Li-xia;ZHENG Hui;Department of Clinical Laboratory,the Second Affiliated Hospital of Xinxiang Medical University;Department of Clinical Laboratory,the Third Affiliated Hospital of Xinxiang Medical University;;Evaluation of serum procalcitonin and C reactive protein level in diagnosis of bacterial infection[J];新乡医学院学报;2015-03
8 Zou Jiangling (Liuyang Traditional Chinese Medicine Hospital,Liuyang,Hunan 410300,China);Prediction of procalcitonin in children with vesicoureteral reflux[J];国际检验医学杂志;2013-02
9 CHEN Juan,Department of Pediatrics,Yunfu People's Hospital,Yunfu 527300,China;Diagnostic value of MCU to check screening for VUR in children[J];国际医药卫生导报;2012-24
10 ZHANG Lin,Xu Dan,ZHOU Zhou,LIU Jian-liang,QIU Bi-bo(Department of Blood Screening Test,Hunan Children's Hospital,Changsha 410007,Hunan China);Diagnostic value of bacterial and white blood cell of non-centrifuged urine in children with urinary tract infection[J];临床儿科杂志;2012-11
【Secondary Citations】
Chinese Journal Full-text Database 9 Hits
1 JIANG Peng,LIANG Ming.Department of Nephrology,Dongying People's Hospital,Dongying,Shangdong 257091,China;Combined Detection of Serum Cystatin-C and Urinary Bata 2 Microglobulin in Patients with Early Diabetic Nephropathy[J];中华全科医学;2011-10
2 LIU Zhi-hui,MENG Qun,SHEN Ying(Department of Nephrology,Beijing Children′s Hospital Affiliated to Capital Medical University,Beijing 100045,China);Acute Kidney Injury in 269 Children[J];实用儿科临床杂志;2011-17
3 LI Ya-wen,WANG Xiao-lei,WANG Chang-lin,SUN Hai-bin,Xia Li-qiao,YU Min (Department of Neonatology,the People′s Hospital of Wuxi City,Wuxi 214000,Jiangsu Province,China);Early diagnostic value of serum cystatin C in kidney injury induced by asphyxia neonatorum[J];新乡医学院学报;2011-04
4 WANG Zheng-yan,SHAN Chun-ming,XU Jun-hua.Department of Pediatrics,The Second People’s Hospital of Huai’an ,Huai’an 223002,China;The value of cystatin C and urine protein/creatinine ratio detection in predicting early renal damage of children with Henoch-Schnlein purpura[J];中国实用儿科杂志;2011-06
5 RUAN Yi-Yan,FENG Jun-Tan,HUANG Zhang-Qiong,QIN Wei-Ling,MOU Jing-Fei.Department of Pediatrics,Maternal and Child Health Hospital,Children′s Hospital of Guangxi,Nanning 530003,China;Diagnostic value of serum Cystatin C in renal function impairments in children with viral encephalitis[J];中国当代儿科杂志;2011-02
6 ZHAO Li-ping,ZHOU Hong-xia,GE Ting-ting,WU Qiao-wei,ZHANG Lin,MEI Bo-ru(Department of Nephrology and Rheumatology,Wuxi Children′s Hospital,Wuxi 214023,Jiangsu Province,China);Urinary Tract Infection in 146 Children[J];实用儿科临床杂志;2010-23
7 XU Hong(Department of Nephrology and Rheumatology,the Children′s Hospital Affiliated to Fudan University,Shanghai 200032,China);Study Progress of Diagnosis and Treatment of Urinary Tract Infection in Children[J];实用儿科临床杂志;2009-17
8 Shanghai Pediatric Nephrology Association and Shanghai Pediatric Urology Association;Consensus of experts on the diagnosis and management of urinary tract infection and vesicoureteric reflux in children(2007 Shanghai)[J];临床儿科杂志;2008-04
9 XU Hong (Department of Nephrology and Rheumatology,The Children's Hospital Affiliated to Fudan University,Shanghai 200032,China);Urinary tract infection and vesicoureteric reflux[J];临床儿科杂志;2008-04
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved