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《Contemporary Medicine》 2017-10
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Clinical effect of the treatment of glucocorticoid induced glaucoma with prostaglandin eye drops

Chen Li-rong;Yao Jun-ping;Zhang Yi-zhuan;Zhou Yu;Gao Bo;Departmen of Ophthalmology, Tianyou Hospital Affliated to Wuhan University of Science and Technology;  
Objective To investigate the clinical effect and mechanism of the treatment of glucocorticoid induced glaucoma in patients with steroid eye drops.Methods In the Kidney medicine Department of 20 IgA nephropathy with average randomized patients with glucocorticoid induced glaucoma,patients in experimental group were treated with prostaglandin eye drops treatment,the control group patients were treated with carteolol hydrochloride eye drops for treatment,of two groups of patients before and after treatment using Goldmann visual field gauge to check the patient's vision and the use of fundus photography is a way to check the optic disc.Results The experimental groupbefore the clinic the 1 man beyond 0.3,7men of the0.1-0.3,2 men of the 0.05-0.1,nobody can’t feel the light,the control group before the clinic 2 man beyond 0.3,5 men of 0.1-0.3,3 men of 0.05-0.1,nobody can’t feel the light.The experimental group before the clinic average visual is(6.83±3.84),intrs-oculst tension is(23.02±1.84),C/D is(0.78±0.03);the control group before the clinic average visual is(6.86±3.31),intrs-oculst tension is(22.98±1.72),C/D is(0.72±0.01);between the two groups don’t has statistical significance.After the clinic the experimental group is the 8 man beyond 0.3,2men of the 0.1-0.3,no one of the 0.05-0.1,nobody can’t feel the light,the 1 man beyond 0.3,7men of the 0.1-0.3,2 men of the 0.05-0.1,nobody can’t feel the light,after clinic control group is 1 man beyond 0.3,4men of the 0.1-0.3,4 men of the 0.05-0.1,1 man can’t feel the light.The experimental group after the clinic average visual is(3.86±3.31),intrs-oculst tension is(22.98±1.72),C/D is(0.72±0.01);the control group before the clinic average visual is(7.90±1.37),intrs-oculst tension is(20.02±1.35),C/D is(0.73±0.04);between the two groups has statistical significance(P﹤0.05).Conclusion The use of prostaglandin eye drops in the treatment of glucocorticoid induced glaucoma and glucocorticoid hormone therapy in patients with a very good therapeutic effect and has an important role in the prognosis of patients.
【CateGory Index】: R775
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