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《Contemporary Medicine》 2017-35
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The effects of Pronase Granules on capsule endoscopy image and lesion detection rate

Liang Chong-fen;Huang Guang-hong;Yao Min-wu;Chen Shu-ni;Department of Gastroenterology, Combine traditional Chinese and Western medicine hospital of Guangdong province;  
Objective To investigate the effects of Pronase Granules on capsule endoscopy image and lesion detection rate. Methods One hundred patients who need capsule endoscopy were randomly divided into the test group(the Pronase Granules group) and control group(blank group).Both groups patients drink compound polyethylene glycolelectrolyte solution for bowel preparation the night before, the next morning before examination, Pronase Granules were given to the test group while none for the control group. The image quality of endoscopy was graded according to air bubble size, clear degree and lesion detection rate, compare the effects of these two different methods. Results In the upper and middle small intestine, the air bubble size and clear degree in test group were significantly better than in control group(P0.05), but in the lower small intestine, they were no significant difference.For the whole small intestine, the clear degree in test group was significantly better than in control group(P0.05),but the air bubble size was no significant difference. Although the test group had higher lesion detection rate, but it was no significant difference than control group. Conclusion Oral Pronase Granules before capsule endoscopy can improve the intestine clear degree, reduce air bubble size, and helpful to increase lesion detection rate.
【Fund】: 佛山市卫生与计生局医学科研课题立项项目(2015291)
【CateGory Index】: R574.5
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